SIGMA CHEMICAL CO -- HEPES BUFFER (1M) ASEPTICALLY FILLED ENDOTOXIN TESTED, H0887  -- 6505-00N092471
<pre>=====================  Product Identification  =====================

Product ID:HEPES BUFFER (1M) ASEPTICALLY FILLED ENDOTOXIN TESTED, H0887
MSDS Date:01/01/1999
FSC:6505
NIIN:00N092471
Status Code:A
MSDS Number: CJTZP
=== Responsible Party ===
Company Name:SIGMA CHEMICAL CO
Box:14508
City:ST LOUIS
State:MO
ZIP:63178
Country:US
Info Phone Num:314-771-5765
Emergency Phone Num:314-771-5765
CAGE:21076
=== Contractor Identification ===
Company Name:SIGMA CHEMICAL COMPANY
Address:3050 SPRUCE ST
Box:14508
City:ST LOUIS
State:MO
ZIP:63178
Country:US
Phone:314-771-5765
CAGE:21076

=============  Composition/Information on Ingredients  =============

Ingred Name:HEPES (BUFFER)
CAS:7365-45-9
RTECS #:TL6809000

=====================  Hazards Identification  =====================

LD50 LC50 Mixture:SEE TOXICOLOGICAL INFORMATION
Routes of Entry: Inhalation:YES  Skin:YES  Ingestion:YES
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:MAY BE HARMFUL BY INHALATION,
    INGESTION OR SKIN ABSORPTION. MAY CAUSE IRRITATION. TO THE BEST OF
    MANUFACTURER'S KNOWLEDGE, THE CHEMICAL, PHYSICAL AND TOXICOLOGICAL
    PROPERTIES HAVE NOT BEEN THOROUGHLY  INVESTIGATED.
Effects of Overexposure:SEE HEALTH HAZARDS.

=======================  First Aid Measures  =======================

First Aid:EYES: IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES WITH COPIOUS
    AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. SKIN: IN CASE OF CONTACT,
    IMMEDIATELY WASH SKIN WITH SOAP AND COPIOUS AMOUNTS OF WATER.
    INHALATI ON: IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE
    ARTIFICIAL RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
    INGESTION: IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON
    IS CONSCIO US. CALL A PHYSICIAN. WASH CONTAMINATED CLOTHING BEFORE
    REUSE.

=====================  Fire Fighting Measures  =====================

Extinguishing Media:WATER SPRAY. CARBON DIOXIDE, DRY CHEMICAL POWDER OR
    APPROPRIATE FOAM.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
    EQUIPMENT  TO PREVENT CONTACT WITH SKIN AND EYES.
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

==================  Accidental Release Measures  ==================

Spill Release Procedures:WEAR NIOSH APPROVED RESPIRATOR, CHEMICAL
    SAFETY GOGGLES, RUBBER BOOTS AND HEAVY RUBBER GLOVES. SWEEP UP,
    PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL. AVOID RAISING DUST.
    VENTILATE AREA AND WASH SPILL S ITE AFTER MATERIAL PICKUP IS
    COMPLETE.

======================	Handling and Storage  ======================

Handling and Storage Precautions:KEEP CONTAINER CLOSED. HYGROSCOPIC.
    STORE IN A COOL, DRY PLACE.
Other Precautions:AVOID BREATHING DUST. AVOID CONTACT WITH EYES, SKIN
    AND CLOTHING. WASH THOROUGHLY AFTER HANDLING. KEEP CONTAINER
    CLOSED.

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:NIOSH APPROVED RESPIRATOR.
Ventilation:MECHANICAL EXHAUST REQUIRED.
Protective Gloves:COMPATIBLE CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:EYE WASH AND DELUGE SHOWER MEETING ANSI
    DESIGN CRITERIA .
Supplemental Safety and Health

==================  Physical/Chemical Properties  ==================

Appearance and Odor:LIQUID.

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
STRONG OXIDIZING AGENTS. PROTECT FROM MOISTURE.
Hazardous Decomposition Products:TOXIC FUMES OF: CARBON MONOXIDE,
    CARBON DIOXIDE. NITROGEN OXIDES. SULFUR OXIDES.

===================  Toxicological Information	===================

Toxicological Information:RTECS #: TL6809000.
    1-PIPERAZINEETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-. TOXICITY
    DATA: ORL-QAL LD50: >316 MG/KG EESADV 6,149,1982. ONLY SELECTED
    REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES (RTE CS) DATA IS
    PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR COMPLETE INFORMATION.

=====================  Ecological Information  =====================

Ecological:DATA NOT YET AVAILABLE.

====================  Disposal Considerations  ====================

Waste Disposal Methods:DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE
    SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN
    AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL
    ENVIRONMENTAL REGULATIONS.

===================  MSDS Transport Information  ===================

Transport Information:CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION
    INFORMATION.

=====================  Regulatory Information  =====================

Federal Regulatory Information:REVIEWS, STANDARDS AND REGULATIONS:
    OEL=MAK. NOES 1983: HZD X9468; NIS 2; TNF 239; NOS 7; TNE 3025; TFE
    2233. EPA TSCA SECTION 8(B) CHEMICAL INVENTORY.

=======================  Other Information  =======================

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 expressly or implied, warrants this information to be accurate and
 disclaims all liability for its use.  Any person utilizing this
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