ACETYLCHOLINE CHLORIDE
MSDS Number: A0830 --- Effective Date: 12/08/96
1. Product Identification
Synonyms: Choline acetate (Ester), chloride;
2-(acetyloxy)-N,N,N-trimethlethanaminium chloride;
acetylcholine, 97%
CAS No.: 60-31-1
Molecular Weight: 181.68
Chemical Formula: (CH3)3N(Cl)(CH2)2OCOCH3
Product Codes: A261
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Acetylcholine Chloride 60-31-1 98 - 100% Yes
3. Hazards Identification
Emergency Overview
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WARNING! CAUSES SEVERE IRRITATION TO EYES, SKIN AND RESPIRATORY
TRACT.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
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Health Rating: 2 - Moderate
Flammability Rating: 1 - Slight
Reactivity Rating: 2 - Moderate
Contact Rating: 2 - Moderate
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES
Storage Color Code: Orange (General Storage)
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Potential Health Effects
----------------------------------
Inhalation:
Causes irritation to the respiratory tract. Symptoms may include coughing,
shortness of breath.
Ingestion:
No information found, but compound should be handled as a potential health
hazard.
Skin Contact:
Causes irritation to skin. Symptoms include redness, itching, and pain.
Eye Contact:
Causes irritation, redness, and pain.
Chronic Exposure:
No information found.
Aggravation of Pre-existing Conditions:
No information found.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Call a physician.
Ingestion:
Induce vomiting immediately as directed by medical personnel. Never give
anything by mouth to an unconscious person. Get medical attention
immediately.
Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes. Remove
contaminated clothing and shoes. Get medical attention. Wash clothing
before reuse. Thoroughly clean shoes before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes,
lifting lower and upper eyelids occasionally. Get medical attention
immediately.
5. Fire Fighting Measures
Fire:
Not considered to be a fire hazard.
Explosion:
Not considered to be an explosion hazard.
Fire Extinguishing Media:
Use any means suitable for extinguishing surrounding fire.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved
self-contained breathing apparatus with full facepiece operated in the
pressure demand or other positive pressure mode.
6. Accidental Release Measures
Ventilate area of leak or spill. Wear appropriate personal protective
equipment as specified in Section 8. Spills: Sweep up and containerize for
reclamation or disposal. Vacuuming or wet sweeping may be used to avoid
dust dispersal.
7. Handling and Storage
Keep in a tightly closed container, stored in a cool, dry, ventilated area.
Protect against physical damage. Isolate from incompatible substances.
Hygroscopic. Protect from moisture. Store under nitrogen. Containers of
this material may be hazardous when empty since they retain product
residues (dust, solids); observe all warnings and precautions listed for
the product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
None established.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee
exposures as low as possible. Local exhaust ventilation is generally
preferred because it can control the emissions of the contaminant at its
source, preventing dispersion of it into the general work area. Please
refer to the ACGIH document, Industrial Ventilation, A Manual of
Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
For conditions of use where exposure to the dust or mist is apparent, a
half-face dust/mist respirator may be worn. For emergencies or instances
where the exposure levels are not known, use a full-face positive-pressure,
air-supplied respirator. WARNING: Air-purifying respirators do not
protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear protective gloves and clean body-covering clothing.
Eye Protection:
Use chemical safety goggles. Maintain eye wash fountain and quick-drench
facilities in work area.
9. Physical and Chemical Properties
Appearance:
Crystalline powder.
Odor:
No information found.
Solubility:
Very soluble in cold water.
Density:
No information found.
pH:
No information found.
% Volatiles by volume @ 21C (70F):
0
Boiling Point:
No information found.
Melting Point:
150 - 152C (302 - 306F)
Vapor Density (Air=1):
No information found.
Vapor Pressure (mm Hg):
No information found.
Evaporation Rate (BuAc=1):
No information found.
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Burning may produce carbon monoxide, carbon dioxide, nitrogen oxides and
hydrogen chloride.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizers and strong bases.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.
11. Toxicological Information
Oral rat LD50: 2500 mg/kg
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Acetylcholine Chloride (60-31-1) No No None
12. Ecological Information
Environmental Fate:
No information found.
Environmental Toxicity:
No information found.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an
appropriate and approved waste disposal facility. Processing, use or
contamination of this product may change the waste management options.
State and local disposal regulations may differ from federal disposal
regulations.
Dispose of container and unused contents in accordance with federal, state
and local requirements.
14. Transport Information
Not regulated.
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Acetylcholine Chloride (60-31-1) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Acetylcholine Chloride (60-31-1) No No Yes Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Acetylcholine Chloride (60-31-1) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Acetylcholine Chloride (60-31-1) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: No Fire: No Pressure: No
Reactivity: No (Pure / Solid)
Australian Hazchem Code: No information found.
Poison Schedule: No information found.
WHMIS:
This MSDS has been prepared according to the hazard criteria of
the Controlled Products Regulations (CPR) and the MSDS contains
all of the information required by the CPR.
16. Other Information
NFPA Ratings:
Health: 2 Flammability: 0 Reactivity: 0
Label Hazard Warning:
WARNING! CAUSES SEVERE IRRITATION TO EYES, SKIN AND RESPIRATORY TRACT.
Label Precautions:
Avoid breathing dust.
Avoid contact with eyes, skin and clothing.
Keep container closed.
Use only with adequate ventilation.
Wash thoroughly after handling.
Label First Aid:
In case of contact, immediately flush eyes or skin with plenty of water for
at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing
before reuse. If inhaled, remove to fresh air. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. If swallowed,
induce vomiting immediately as directed by medical personnel. Never give
anything by mouth to an unconscious person. In all cases, get medical
attention.
Product Use:
Laboratory Reagent.
Revision Information:
Pure. New 16 section MSDS format, all sections have been revised.
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in good
faith but makes no representation as to its comprehensiveness or accuracy. This
document is intended only as a guide to the appropriate precautionary handling
of the material by a properly trained person using this product. Individuals
receiving the information must exercise their independent judgment in
determining its appropriateness for a particular purpose. MALLINCKRODT BAKER,
INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED,
INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A
PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE
PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC.
WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS
INFORMATION.
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Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)