Acrolein

MSDS Number: A1538 --- Effective Date: 12/08/96


1. Product Identification

Synonyms: Acraldehyde; Acrylic Aldehyde; Allyl Aldehyde; Ethylene Aldehyde; 2-Propenal
CAS No.: 107-02-8
Molecular Weight: 56.06
Chemical Formula: CH2:CHCHO
Product Codes: A384


2. Composition/Information on Ingredients


  Ingredient                                CAS No         Percent   Hazardous                                       
  ---------------------------------------   ------------   -------   ---------        
 
  Acrolein                                  107-02-8       90 - 100%    Yes                                                                  
 


3. Hazards Identification

Emergency Overview
--------------------------
POISON! DANGER! MAY BE FATAL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. CAUSES SEVERE IRRITATION TO EYES, SKIN AND RESPIRATORY TRACT. AFFECTS THE HEART. MAY CAUSE LUNG DAMAGE. EXTREMELY FLAMMABLE LIQUID AND VAPOR. VAPOR MAY CAUSE FLASH FIRE. MAY FORM EXPLOSIVE PEROXIDES.


J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 3 - Severe (Poison)
Flammability Rating: 3 - Severe (Flammable)
Reactivity Rating: 2 - Moderate
Contact Rating: 4 - Extreme (Corrosive)
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER GLOVES; CLASS B EXTINGUISHER
Storage Color Code: Red (Flammable)
-----------------------------------------------------------------------------------------------------------

Potential Health Effects
----------------------------------

Inhalation:
Toxic. Highly irritating. It can injure the lungs and bronchial airways. Symptoms include severe irritation of the mucous membranes, burning of the throat, cough, difficulty breathing, tightness in the chest, nausea, vomiting and diarrhea, pulmonary edema, high blood pressure, and unconsciousness. A weak sensitizer; may cause asthmatic reaction. Inhalation of high concentrations can cause permanent lung damage. Fatalities have occurred from exposure to levels as low as 10 ppm; 1 ppm produces marked eye, respiratory, and mucous membrane irritation in less than 5 minutes.

Ingestion:
May produce severe irritation of the mouth and gastrointestinal tract.

Skin Contact:
Causes severe irritation with redness, pain, and possibly skin burns. Contact may cause sensitization dermatitis.

Eye Contact:
Causes severe irritation, extensive tearing, pus-like discharge, corneal damage and damage to area around eyelids. May cause corneal burns.

Chronic Exposure:
The violent irritating effects of acrolein generally prevents any chronic toxicity. Repeated inhalation can sensitize some individuals resulting in an asthmatic response.

Aggravation of Pre-existing Conditions:
Persons with pre-existing respiratory disorders may be more susceptible to the effects of this substance.


4. First Aid Measures

Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention immediately. Prompt action is essential.

Ingestion:
Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention immediately.

Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention immediately. Wash clothing before reuse. Thoroughly clean shoes before reuse.

Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.


5. Fire Fighting Measures

Fire:
Flash point: -26C (-15F) CC Autoignition temperature: 235C (455F) Flammable limits in air % by volume: lel: 2.8; uel: 31.0 Extremely Flammable Liquid and Vapor! Vapor may cause flash fire. Contact with strong oxidizers may cause fire.

Explosion:
Vapors can flow along surfaces to distant ignition source and flash back. Vapor may polymerize explosively at elevated temperatures. Closed containers exposed to heat may explode.

Fire Extinguishing Media:
Use dry chemical, carbon dioxide, "alcohol-resistant" foam, or flooding quantities of water. Do not get water inside container because of exothermic reaction; water can be used to fight fires because in flooding quantities, excessive heat will not be generated. Do not release runoff from fire control methods to sewers or waterways.

Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.


6. Accidental Release Measures

Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel from entering. Contain and recover liquid when possible. Use non-sparking tools and equipment. Collect liquid in an appropriate container or absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a chemical waste container. Do not use combustible materials, such as saw dust. Do not flush to sewer! US Regulations (CERCLA) require reporting spills and releases to soil, water and air in excess of reportable quantities. The toll free number for the US Coast Guard National Response Center is (800) 424-8802.


7. Handling and Storage

Protect from direct sunlight. Protect against physical damage. Store in a cool, dry well-ventilated location, away from any area where the fire hazard may be acute. Outside or detached storage is preferred. Separate from incompatibles. Containers should be bonded and grounded for transfers to avoid static sparks. Storage and use areas should be No Smoking areas. Use non-sparking type tools and equipment, including explosion proof ventilation. Inside storage should be in a standard flammable liquids storage room or cabinet. No alkaline material such as caustics, ammonia, or amines or oxidizing materials permitted in storage room or cabinets. Do not store acrolein uninhibited under any circumstances. Containers of this material may be hazardous when empty since they retain product residues (vapors, liquid); observe all warnings and precautions listed for the product.


8. Exposure Controls/Personal Protection

Airborne Exposure Limits:
- OSHA Permissible Exposure Limit (PEL): 0.1 ppm (TWA) . - ACGIH Threshold Limit Value (TLV): 0.1 ppm (TWA); 0.3 ppm (STEL).

Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.

Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded, wear a supplied air, full-facepiece respirator, airlined hood, or full-facepiece self-contained breathing apparatus.

Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.

Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.


9. Physical and Chemical Properties

Appearance:
Colorless to yellow liquid.

Odor:
Irritating odor.

Solubility:
Appreciable (>10%)

Specific Gravity:
0.84 @ 20C/4C

pH:
6 (10% solution)

% Volatiles by volume @ 21C (70F):
100

Boiling Point:
53C (127F)

Melting Point:
-88C (-126F)

Vapor Density (Air=1):
1.94

Vapor Pressure (mm Hg):
210 @ 20C (68F)

Evaporation Rate (BuAc=1):
No information found.


10. Stability and Reactivity

Stability:
Unstable. Polymerizes. Forms explosive peroxides upon standing.

Hazardous Decomposition Products:
Carbon monoxide and peroxides.

Hazardous Polymerization:
Polymerizes readily unless inhibited (usually with hydroquinone). Hazardous polymerization can occur from exposure to heat, sunlight, acid, or alkalis. Formation of peroxides over time can also lead to polymerization. Reaction may be violent.

Incompatibilities:
Reacts with acids, amines, alkalis, sulfur dioxide, metal salts, oxidants, thiourea, dimethylamine, or weak acid conditions such as nitrogen or carbon oxide gases. Reactions may be very rapid and violent.

Conditions to Avoid:
Insufficient inhibitor, heat, flame, ignition sources, sunlight, air and incompatibles.


11. Toxicological Information

Toxicological Data:
- Toxicological Data - Oral rat LD50: 26 mg/kg; Inhalation rat LC50: 18 mg/m3 / 4 H; Skin rabbit LD50: 200 mg/kg. - Irritation Data - Skin rabbit (std Draize, 2 mg / 24 H): Severe; Skin rabbit (open Draize, 5 mg): Severe; Eye rabbit (std Draize, 50 ug / 24 H): Severe; Eye rabbit (std Draize, 1 mg): Severe. Investigated as a tumorigen, mutagen, reproductive effector.

Carcinogenicity:
EPA / IRIS classification: Group C - Possible human carcinogen.

  --------\Cancer Lists\------------------------------------------------------
                                         ---NTP Carcinogen---
  Ingredient                             Known    Anticipated    IARC Category
  ------------------------------------   -----    -----------    -------------
  Acrolein (107-02-8)                     No          No              3


12. Ecological Information

Environmental Fate:
When released into the soil, this material may biodegrade to a moderate extent. When released into the soil, this material is expected to leach into groundwater. When released into the soil, this material is expected to quickly evaporate. When released into water, this material may biodegrade to a moderate extent. When released to water, this material is expected to quickly evaporate. When released into the water, this material is expected to have a half-life between 1 and 10 days. This material is not expected to significantly bioaccumulate. When released into the air, this material is expected to be readily degraded by reaction with photochemically produced hydroxyl radicals. When released into the air, this material is not expected to be degraded by photolysis. When released into the air, this material may be removed from the atmosphere to a moderate extent by wet deposition.

Environmental Toxicity:
This material is expected to be very toxic to aquatic life. The LC50/96-hour values for fish are less than 1 mg/l.


13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and sent to a RCRA approved waste facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.


14. Transport Information

Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: ACROLEIN, INHIBITED, TOXIC-INHALATION HAZARD ZONE A
Hazard Class: 6.1, 3
UN/NA: UN1092
Packing Group: I
Information reported for product/size: 250ML

International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: ACROLEIN, INHIBITED
Hazard Class: 6.1, 3.1
UN/NA: UN1092
Packing Group: I
Information reported for product/size: 250ML

International (Air, I.C.A.O.)
-----------------------------
Proper Shipping Name: ACROLEIN, INHIBITED
Hazard Class: 6.1, 3.1
UN/NA: UN1092
Packing Group: I
Information reported for product/size: 250ML



15. Regulatory Information


  --------\Chemical Inventory Status - Part 1\---------------------------------
  Ingredient                                       TSCA  EC   Japan  Australia
  -----------------------------------------------  ----  ---  -----  ---------
  Acrolein (107-02-8)                               Yes  Yes   Yes      Yes                                      
 
  --------\Chemical Inventory Status - Part 2\---------------------------------
                                                          --Canada--
  Ingredient                                       Korea  DSL   NDSL  Phil.
  -----------------------------------------------  -----  ---   ----  -----
  Acrolein (107-02-8)                               Yes   Yes   No     Yes                             
 
  --------\Federal, State & International Regulations - Part 1\----------------
                                             -SARA 302-    ------SARA 313------
  Ingredient                                 RQ    TPQ     List  Chemical Catg.
  -----------------------------------------  ---   -----   ----  --------------
  Acrolein (107-02-8)                        1     500     Yes        No
 
  --------\Federal, State & International Regulations - Part 2\----------------
                                                        -RCRA-    -TSCA-
  Ingredient                                 CERCLA     261.33     8(d) 
  -----------------------------------------  ------     ------    ------
  Acrolein (107-02-8)                        1          P003       Yes                  
 
 
Chemical Weapons Convention:  No     TSCA 12(b):  No     CDTA:  No
SARA 311/312:  Acute: Yes      Chronic: Yes  Fire: Yes Pressure: No
Reactivity: Yes         (Pure / Liquid) 


Australian Hazchem Code: 2WE
Poison Schedule: No information found.

WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.


16. Other Information

NFPA Ratings: Health: 4 Flammability: 3 Reactivity: 3

Label Hazard Warning:
POISON! DANGER! MAY BE FATAL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. CAUSES SEVERE IRRITATION TO EYES, SKIN AND RESPIRATORY TRACT. AFFECTS THE HEART. MAY CAUSE LUNG DAMAGE. EXTREMELY FLAMMABLE LIQUID AND VAPOR. VAPOR MAY CAUSE FLASH FIRE. MAY FORM EXPLOSIVE PEROXIDES.

Label Precautions:
May form explosive peroxides. Keep away from heat, sparks and flame. Keep container closed. Use only with adequate ventilation. Do not breathe vapor or mist. Do not get in eyes, on skin, or on clothing. Wash thoroughly after handling.

Label First Aid:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. If swallowed, induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. In all cases get medical attention immediately.

Product Use:
Laboratory Reagent.

Revision Information:
Pure. New 16 section MSDS format, all sections have been revised.

Disclaimer:
************************************************************************************************ Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
************************************************************************************************ Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)