Acrolein
MSDS Number: A1538 --- Effective Date: 12/08/96
1. Product Identification
Synonyms: Acraldehyde; Acrylic Aldehyde; Allyl Aldehyde; Ethylene
Aldehyde; 2-Propenal
CAS No.: 107-02-8
Molecular Weight: 56.06
Chemical Formula: CH2:CHCHO
Product Codes: A384
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Acrolein 107-02-8 90 - 100% Yes
3. Hazards Identification
Emergency Overview
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POISON! DANGER! MAY BE FATAL IF SWALLOWED, INHALED OR ABSORBED THROUGH
SKIN. CAUSES SEVERE IRRITATION TO EYES, SKIN AND RESPIRATORY TRACT. AFFECTS
THE HEART. MAY CAUSE LUNG DAMAGE. EXTREMELY FLAMMABLE LIQUID AND VAPOR.
VAPOR MAY CAUSE FLASH FIRE. MAY FORM EXPLOSIVE PEROXIDES.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
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Health Rating: 3 - Severe (Poison)
Flammability Rating: 3 - Severe (Flammable)
Reactivity Rating: 2 - Moderate
Contact Rating: 4 - Extreme (Corrosive)
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER
GLOVES; CLASS B EXTINGUISHER
Storage Color Code: Red (Flammable)
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Potential Health Effects
----------------------------------
Inhalation:
Toxic. Highly irritating. It can injure the lungs and bronchial airways.
Symptoms include severe irritation of the mucous membranes, burning of the
throat, cough, difficulty breathing, tightness in the chest, nausea,
vomiting and diarrhea, pulmonary edema, high blood pressure, and
unconsciousness. A weak sensitizer; may cause asthmatic reaction.
Inhalation of high concentrations can cause permanent lung damage.
Fatalities have occurred from exposure to levels as low as 10 ppm; 1 ppm
produces marked eye, respiratory, and mucous membrane irritation in less
than 5 minutes.
Ingestion:
May produce severe irritation of the mouth and gastrointestinal tract.
Skin Contact:
Causes severe irritation with redness, pain, and possibly skin burns.
Contact may cause sensitization dermatitis.
Eye Contact:
Causes severe irritation, extensive tearing, pus-like discharge, corneal
damage and damage to area around eyelids. May cause corneal burns.
Chronic Exposure:
The violent irritating effects of acrolein generally prevents any chronic
toxicity. Repeated inhalation can sensitize some individuals resulting in
an asthmatic response.
Aggravation of Pre-existing Conditions:
Persons with pre-existing respiratory disorders may be more susceptible to
the effects of this substance.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical attention immediately.
Prompt action is essential.
Ingestion:
Induce vomiting immediately as directed by medical personnel. Never give
anything by mouth to an unconscious person. Get medical attention
immediately.
Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes while
removing contaminated clothing and shoes. Get medical attention
immediately. Wash clothing before reuse. Thoroughly clean shoes before
reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes,
lifting lower and upper eyelids occasionally. Get medical attention
immediately.
5. Fire Fighting Measures
Fire:
Flash point: -26C (-15F) CC
Autoignition temperature: 235C (455F)
Flammable limits in air % by volume:
lel: 2.8; uel: 31.0
Extremely Flammable Liquid and Vapor! Vapor may cause flash fire.
Contact with strong oxidizers may cause fire.
Explosion:
Vapors can flow along surfaces to distant ignition source and flash back.
Vapor may polymerize explosively at elevated temperatures. Closed
containers exposed to heat may explode.
Fire Extinguishing Media:
Use dry chemical, carbon dioxide, "alcohol-resistant" foam, or flooding
quantities of water. Do not get water inside container because of
exothermic reaction; water can be used to fight fires because in flooding
quantities, excessive heat will not be generated. Do not release runoff
from fire control methods to sewers or waterways.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved
self-contained breathing apparatus with full facepiece operated in the
pressure demand or other positive pressure mode.
6. Accidental Release Measures
Ventilate area of leak or spill. Remove all sources of ignition. Wear
appropriate personal protective equipment as specified in Section 8.
Isolate hazard area. Keep unnecessary and unprotected personnel from
entering. Contain and recover liquid when possible. Use non-sparking tools
and equipment. Collect liquid in an appropriate container or absorb with an
inert material (e. g., vermiculite, dry sand, earth), and place in a
chemical waste container. Do not use combustible materials, such as saw
dust. Do not flush to sewer! US Regulations (CERCLA) require reporting
spills and releases to soil, water and air in excess of reportable
quantities. The toll free number for the US Coast Guard National Response
Center is (800) 424-8802.
7. Handling and Storage
Protect from direct sunlight. Protect against physical damage. Store in a
cool, dry well-ventilated location, away from any area where the fire
hazard may be acute. Outside or detached storage is preferred. Separate
from incompatibles. Containers should be bonded and grounded for transfers
to avoid static sparks. Storage and use areas should be No Smoking areas.
Use non-sparking type tools and equipment, including explosion proof
ventilation. Inside storage should be in a standard flammable liquids
storage room or cabinet. No alkaline material such as caustics, ammonia, or
amines or oxidizing materials permitted in storage room or cabinets. Do not
store acrolein uninhibited under any circumstances. Containers of this
material may be hazardous when empty since they retain product residues
(vapors, liquid); observe all warnings and precautions listed for the
product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
- OSHA Permissible Exposure Limit (PEL):
0.1 ppm (TWA) .
- ACGIH Threshold Limit Value (TLV):
0.1 ppm (TWA); 0.3 ppm (STEL).
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee
exposures below the Airborne
Exposure Limits. Local exhaust ventilation is generally preferred because
it can control the emissions of the contaminant at its source, preventing
dispersion of it into the general work area. Please refer to the ACGIH
document, Industrial Ventilation, A Manual of Recommended Practices,
most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded, wear a supplied air, full-facepiece
respirator, airlined hood, or full-facepiece self-contained breathing
apparatus.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat,
apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is
possible. Maintain eye wash fountain and quick-drench facilities in work
area.
9. Physical and Chemical Properties
Appearance:
Colorless to yellow liquid.
Odor:
Irritating odor.
Solubility:
Appreciable (>10%)
Specific Gravity:
0.84 @ 20C/4C
pH:
6 (10% solution)
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
53C (127F)
Melting Point:
-88C (-126F)
Vapor Density (Air=1):
1.94
Vapor Pressure (mm Hg):
210 @ 20C (68F)
Evaporation Rate (BuAc=1):
No information found.
10. Stability and Reactivity
Stability:
Unstable. Polymerizes. Forms explosive peroxides upon standing.
Hazardous Decomposition Products:
Carbon monoxide and peroxides.
Hazardous Polymerization:
Polymerizes readily unless inhibited (usually with hydroquinone).
Hazardous polymerization can occur from exposure to heat, sunlight, acid,
or alkalis. Formation of peroxides over time can also lead to
polymerization. Reaction may be violent.
Incompatibilities:
Reacts with acids, amines, alkalis, sulfur dioxide, metal salts, oxidants,
thiourea, dimethylamine, or weak acid conditions such as nitrogen or carbon
oxide gases. Reactions may be very rapid and violent.
Conditions to Avoid:
Insufficient inhibitor, heat, flame, ignition sources, sunlight, air and
incompatibles.
11. Toxicological Information
Toxicological Data:
- Toxicological Data -
Oral rat LD50: 26 mg/kg;
Inhalation rat LC50: 18 mg/m3 / 4 H;
Skin rabbit LD50: 200 mg/kg.
- Irritation Data -
Skin rabbit (std Draize, 2 mg / 24 H): Severe;
Skin rabbit (open Draize, 5 mg): Severe;
Eye rabbit (std Draize, 50 ug / 24 H): Severe;
Eye rabbit (std Draize, 1 mg): Severe.
Investigated as a tumorigen, mutagen, reproductive effector.
Carcinogenicity:
EPA / IRIS classification: Group C - Possible human carcinogen.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Acrolein (107-02-8) No No 3
12. Ecological Information
Environmental Fate:
When released into the soil, this material may biodegrade to a moderate
extent. When released into the soil, this material is expected to leach
into groundwater. When released into the soil, this material is expected to
quickly evaporate. When released into water, this material may biodegrade
to a moderate extent. When released to water, this material is expected to
quickly evaporate. When released into the water, this material is expected
to have a half-life between 1 and 10 days. This material is not expected to
significantly bioaccumulate. When released into the air, this material is
expected to be readily degraded by reaction with photochemically produced
hydroxyl radicals. When released into the air, this material is not
expected to be degraded by photolysis. When released into the air, this
material may be removed from the atmosphere to a moderate extent by wet
deposition.
Environmental Toxicity:
This material is expected to be very toxic to aquatic life. The
LC50/96-hour values for fish are less than 1 mg/l.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be handled as
hazardous waste and sent to a RCRA approved waste facility. Processing, use
or contamination of this product may change the waste management options.
State and local disposal regulations may differ from federal disposal
regulations.
Dispose of container and unused contents in accordance with federal, state
and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: ACROLEIN, INHIBITED, TOXIC-INHALATION HAZARD ZONE A
Hazard Class: 6.1, 3
UN/NA: UN1092
Packing Group: I
Information reported for product/size: 250ML
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: ACROLEIN, INHIBITED
Hazard Class: 6.1, 3.1
UN/NA: UN1092
Packing Group: I
Information reported for product/size: 250ML
International (Air, I.C.A.O.)
-----------------------------
Proper Shipping Name: ACROLEIN, INHIBITED
Hazard Class: 6.1, 3.1
UN/NA: UN1092
Packing Group: I
Information reported for product/size: 250ML
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Acrolein (107-02-8) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Acrolein (107-02-8) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Acrolein (107-02-8) 1 500 Yes No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Acrolein (107-02-8) 1 P003 Yes
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: Yes Pressure: No
Reactivity: Yes (Pure / Liquid)
Australian Hazchem Code: 2WE
Poison Schedule: No information found.
WHMIS:
This MSDS has been prepared according to the hazard criteria of
the Controlled Products Regulations (CPR) and the MSDS contains
all of the information required by the CPR.
16. Other Information
NFPA Ratings:
Health: 4 Flammability: 3 Reactivity: 3
Label Hazard Warning:
POISON! DANGER! MAY BE FATAL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN.
CAUSES SEVERE IRRITATION TO EYES, SKIN AND RESPIRATORY TRACT. AFFECTS THE
HEART. MAY CAUSE LUNG DAMAGE. EXTREMELY FLAMMABLE LIQUID AND VAPOR. VAPOR
MAY CAUSE FLASH FIRE. MAY FORM EXPLOSIVE PEROXIDES.
Label Precautions:
May form explosive peroxides.
Keep away from heat, sparks and flame.
Keep container closed.
Use only with adequate ventilation.
Do not breathe vapor or mist.
Do not get in eyes, on skin, or on clothing.
Wash thoroughly after handling.
Label First Aid:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. If swallowed, induce
vomiting immediately as directed by medical personnel. Never give anything by
mouth to an unconscious person. In case of contact, immediately flush eyes or
skin with plenty of water for at least 15 minutes while removing contaminated
clothing and shoes. Wash clothing before reuse. In all cases get medical
attention immediately.
Product Use:
Laboratory Reagent.
Revision Information:
Pure. New 16 section MSDS format, all sections have been revised.
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in good
faith but makes no representation as to its comprehensiveness or accuracy. This
document is intended only as a guide to the appropriate precautionary handling
of the material by a properly trained person using this product. Individuals
receiving the information must exercise their independent judgment in
determining its appropriateness for a particular purpose. MALLINCKRODT BAKER,
INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED,
INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A
PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE
PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC.
WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS
INFORMATION.
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Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)