ANILINE HYDROCHLORIDE

MSDS Number: A6684 --- Effective Date: 12/08/96


1. Product Identification

Synonyms: Benzenamine, hydrochloride; aniline chloride; aniline salt
CAS No.: 142-04-1
Molecular Weight: 129.60
Chemical Formula: C6H8NCl
Product Codes: 1851


2. Composition/Information on Ingredients


  Ingredient                                CAS No         Percent   Hazardous                                       
  ---------------------------------------   ------------   -------   ---------        
 
  Aniline Hydrochloride                     142-04-1       90 - 100%    Yes                                                                  
 


3. Hazards Identification

Emergency Overview
--------------------------
DANGER! MAY BE FATAL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT. MAY CAUSE CYANOSIS.


Potential Health Effects
----------------------------------

Inhalation:
Toxic. Affects ability of blood to carry oxygen. Symptoms may include bluish discoloration of lips and tongue, severe headache, nausea, confusion, dizziness, shock, respiratory paralysis, death.

Ingestion:
Toxic. Lethal dose may be as little as one gram. Symptoms of ingestion parallel those of inhalation exposure.

Skin Contact:
May be absorbed through skin. Symptoms of skin absorption parallel those from inhalation exposure. Local contact may cause dermatitis.

Eye Contact:
Vapor is an eye irritant. Splashes may cause corneal damage.

Chronic Exposure:
Aniline is a blood toxin, causing hemoglobin to convert to methemoglobin, resulting in cyanosis. Lengthy or repeated exposures may result in decreased appetite, anemia, weight loss, nervous system affects, and kidney, liver and bone marrow damage.

Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders or eye problems or impaired liver or kidney function may be more susceptible to the effects of the substance.


4. First Aid Measures

Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention immediately.

Ingestion:
Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention immediately.

Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention immediately. Wash clothing before reuse. Thoroughly clean shoes before reuse.

Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.


5. Fire Fighting Measures

Fire:
Flash point: 193C (379F) CC Slight fire hazard when exposed to heat or flame.

Explosion:
Above the flash point, explosive vapor-air mixtures may be formed.

Fire Extinguishing Media:
Water spray, dry chemical, alcohol foam, or carbon dioxide.

Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.


6. Accidental Release Measures

Remove all sources of ignition. Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Spills: Clean up spills in a manner that does not disperse dust into the air. Use non-sparking tools and equipment. Reduce airborne dust and prevent scattering by moistening with water. Pick up spill for recovery or disposal and place in a closed container.


7. Handling and Storage

Keep in a tightly closed light-resistant container, stored in a cool, dry, ventilated area. Protect against physical damage. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product.


8. Exposure Controls/Personal Protection

Airborne Exposure Limits:
For Parent Compound Aniline: -OSHA Permissible Exposure Limit (PEL): 2 ppm (TWA) skin -ACGIH Threshold Limit Value (TLV): 2 ppm (TWA) skin

Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.

Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded, wear a supplied air, full-facepiece respirator, airlined hood, or full-facepiece self-contained breathing apparatus.

Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.

Eye Protection:
Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.

Other Control Measures:
Provide clean work clothes daily to workers who regularly use this material. Wash hands before eating and do not eat, drink, or smoke in workplace.


9. Physical and Chemical Properties

Appearance:
White to yellow crystals. Darkens on exposure to light or air.

Odor:
Weakly amine.

Solubility:
Soluble in water.

Specific Gravity:
1.222

pH:
No information found.

% Volatiles by volume @ 21C (70F):
0

Boiling Point:
245C (473F)

Melting Point:
198 - 199C (388 - 390F)

Vapor Density (Air=1):
4.46

Vapor Pressure (mm Hg):
No information found.

Evaporation Rate (BuAc=1):
No information found.


10. Stability and Reactivity

Stability:
Stable under ordinary conditions of use and storage. Darkens on exposure to air or light.

Hazardous Decomposition Products:
Burning may produce carbon monoxide, carbon dioxide, nitrogen oxides.

Hazardous Polymerization:
Will not occur.

Incompatibilities:
Strong oxidizers. Strong oxidizers and strong acids.

Conditions to Avoid:
Heat, flame, ignition sources, dusting, air, light and incompatibles.


11. Toxicological Information


Oral rat LD50: 840 mg/kg. Irritation, rabbit, std Draize: eye= 20mg/24 H, moderate; skin= 500mg/24H, moderate. Investigated as a tumorigen, mutagen, reproductive effector.

  --------\Cancer Lists\------------------------------------------------------
                                         ---NTP Carcinogen---
  Ingredient                             Known    Anticipated    IARC Category
  ------------------------------------   -----    -----------    -------------
  Aniline Hydrochloride (142-04-1)        No          No            None


12. Ecological Information

Environmental Fate:
No information found.

Environmental Toxicity:
No information found.


13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.


14. Transport Information

Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: ANILINE HYDROCHLORIDE
Hazard Class: 6.1
UN/NA: UN1548
Packing Group: III
Information reported for product/size: 100G

International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: ANILINE HYDROCHLORIDE
Hazard Class: 6.1
UN/NA: UN1548
Packing Group: III
Information reported for product/size: 100G



15. Regulatory Information


  --------\Chemical Inventory Status - Part 1\---------------------------------
  Ingredient                                       TSCA  EC   Japan  Australia
  -----------------------------------------------  ----  ---  -----  ---------
  Aniline Hydrochloride (142-04-1)                  Yes  Yes   Yes      Yes                                      
 
  --------\Chemical Inventory Status - Part 2\---------------------------------
                                                          --Canada--
  Ingredient                                       Korea  DSL   NDSL  Phil.
  -----------------------------------------------  -----  ---   ----  -----
  Aniline Hydrochloride (142-04-1)                  No    Yes   No     Yes                             
 
  --------\Federal, State & International Regulations - Part 1\----------------
                                             -SARA 302-    ------SARA 313------
  Ingredient                                 RQ    TPQ     List  Chemical Catg.
  -----------------------------------------  ---   -----   ----  --------------
  Aniline Hydrochloride (142-04-1)           No    No      No         No
 
  --------\Federal, State & International Regulations - Part 2\----------------
                                                        -RCRA-    -TSCA-
  Ingredient                                 CERCLA     261.33     8(d) 
  -----------------------------------------  ------     ------    ------
  Aniline Hydrochloride (142-04-1)           No         No         No                   
 
 
Chemical Weapons Convention:  No     TSCA 12(b):  No     CDTA:  No
SARA 311/312:  Acute: Yes      Chronic: Yes  Fire: No  Pressure: No
Reactivity: No          (Pure / Solid) 


Australian Hazchem Code: 2Z
Poison Schedule: No information found.

WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.


16. Other Information

NFPA Ratings: Health: 3 Flammability: 1 Reactivity: 0

Label Hazard Warning:
DANGER! MAY BE FATAL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT. MAY CAUSE CYANOSIS.

Label Precautions:
Do not breathe dust. Do not get in eyes, on skin, or on clothing. Keep container closed. Use only with adequate ventilation. Wash thoroughly after handling.

Label First Aid:
If swallowed, induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. In all cases get medical attention immediately.

Product Use:
Laboratory Reagent.

Revision Information:
Pure. New 16 section MSDS format, all sections have been revised.

Disclaimer:
************************************************************************************************ Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
************************************************************************************************ Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)