2-BUTOXYETHANOL
MSDS Number: B6100 --- Effective Date: 12/08/96
1. Product Identification
Synonyms: Butyl cellosolve(tm); Ethylene glycol monobutyl ether
CAS No.: 111-76-2
Molecular Weight: 118.18
Chemical Formula: HOCH2CH2OC4H9
Product Codes: J.T. Baker:
D648, D649
Mallinckrodt:
2138
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
2-Butoxyethanol 111-76-2 99 - 100% Yes
3. Hazards Identification
Emergency Overview
--------------------------
WARNING! HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. CAUSES
EYE IRRITATION. AFFECTS CENTRAL NERVOUS SYSTEM, BLOOD AND BLOOD-FORMING
ORGANS, KIDNEYS, LIVER AND LYMPHOID SYSTEM. COMBUSTIBLE LIQUID AND VAPOR.
MAY CAUSE IRRITATION TO SKIN AND RESPIRATORY TRACT.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 2 - Moderate
Flammability Rating: 2 - Moderate
Reactivity Rating: 1 - Slight
Contact Rating: 3 - Severe (Life)
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER
GLOVES; CLASS B EXTINGUISHER
Storage Color Code: Red (Flammable)
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Potential Health Effects
----------------------------------
Inhalation:
Causes irritation to the respiratory tract. Symptoms may include sore
throat, coughing, headache, nausea and shortness of breath. High
concentrations have a narcotic effect.
Ingestion:
Causes irritation to the gastrointestinal tract. Symptoms may include
nausea, vomiting and diarrhea. Toxic! May cause systemic poisoning with
symptoms paralleling those of inhalation.
Skin Contact:
May cause irritation with redness and pain. May be absorbed through the
skin with possible systemic effects.
Eye Contact:
Vapors are irritating and may produce immediate pain, redness and tearing.
Splashes can cause severe pain, stinging, swelling.
Chronic Exposure:
Prolonged or repeated exposures can cause damage to the liver, kidneys,
lymphoid system, blood and blood-forming organs.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders, eye problems, impaired liver,
kidney, blood, respiratory or lymphoid system function may be more
susceptible to the effects of the substance.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Call a physician immediately.
Ingestion:
Induce vomiting immediately as directed by medical personnel. Never give
anything by mouth to an unconscious person. Call a physician immediately.
Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes while
removing contaminated clothing and shoes. Call a physician, immediately.
Wash clothing before reuse.
Eye Contact:
Immediately flush eyes with gentle but large stream of water for at least
15 minutes, lifting lower and upper eyelids occasionally. Call a physician
immediately.
5. Fire Fighting Measures
Fire:
Flash point: 62C (144F)
Autoignition temperature: 238C (460F)
Flammable limits in air % by volume:
lel: 1.1; uel: 12.7
Combustible Liquid.
Explosion:
Above flash point, vapor-air mixtures are explosive within flammable limits
noted above. Vapors can flow along surfaces to distant ignition source and
flash back. Contact with strong oxidizers may cause fire. Sensitive to
static discharge.
Fire Extinguishing Media:
Dry chemical, alcohol foam or carbon dioxide. Do not use a solid stream of
water, since the stream will scatter and spread the fire. Water spray may
be used to keep fire exposed containers cool, dilute spills to nonflammable
mixtures, protect personnel attempting to stop leak and disperse vapors.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved
self-contained breathing apparatus with full facepiece operated in the
pressure demand or other positive pressure mode.
6. Accidental Release Measures
Ventilate area of leak or spill. Remove all sources of ignition. Wear
appropriate personal protective equipment as specified in Section 8.
Isolate hazard area. Keep unnecessary and unprotected personnel from
entering. Contain and recover liquid when possible. Use non-sparking tools
and equipment. Collect liquid in an appropriate container or absorb with an
inert material (e. g., vermiculite, dry sand, earth), and place in a
chemical waste container. Do not use combustible materials, such as saw
dust. Do not flush to sewer! If a leak or spill has not ignited, use water
spray to disperse the vapors, to protect personnel attempting to stop leak,
and to flush spills away from exposures.
J. T. Baker SOLUSORB(tm) solvent adsorbent is recommended for spills of
this product.
7. Handling and Storage
Protect against physical damage. Store in a cool, dry well-ventilated
location, away from any area where the fire hazard may be acute. Outside or
detached storage is preferred. Separate from oxidizing materials.
Containers should be bonded and grounded for transfers to avoid static
sparks. Storage and use areas should be No Smoking areas. Containers of
this material may be hazardous when empty since they retain product
residues (vapors, liquid); observe all warnings and precautions listed for
the product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
-OSHA Permissible Exposure Limit (PEL):
50 ppm skin
-ACGIH Threshold Limit Value (TLV):
25 ppm (TWA) skin
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee
exposures below the Airborne
Exposure Limits. Local exhaust ventilation is generally preferred because
it can control the emissions of the contaminant at its source, preventing
dispersion of it into the general work area. Please refer to the ACGIH
document, Industrial Ventilation, A Manual of Recommended Practices,
most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded, a full facepiece respirator with organic
vapor cartridge may be worn up to 50 times the exposure limit or the
maximum use concentration specified by the appropriate regulatory agency or
respirator supplier, whichever is lowest. For emergencies or instances
where the exposure levels are not known, use a full-facepiece
positive-pressure, air-supplied respirator. WARNING: Air purifying
respirators do not protect workers in oxygen-deficient atmospheres. This
compound possibly exists in both particulate and vapor phase. A dust/mist
prefilter should be used for the particulate.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat,
apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is
possible. Maintain eye wash fountain and quick-drench facilities in work
area.
9. Physical and Chemical Properties
Appearance:
Clear, colorless liquid.
Odor:
Mild odor.
Solubility:
Soluble in water.
Specific Gravity:
0.90 @ 20C/4C
pH:
No information found.
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
171C (340F)
Melting Point:
-70C (-94F)
Vapor Density (Air=1):
4.07
Vapor Pressure (mm Hg):
0.8 @ 20C (68F)
Evaporation Rate (BuAc=1):
0.07
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizers, strong bases. May attack metallic aluminum at high
temperatures.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.
11. Toxicological Information
Toxicological Data:
Oral rat LD50: 470 mg/kg; Inhalation rat LC50: 450ppm/4H; Skin rabbit
LD50: 220 mg/kg; investigated as a tumorigen, mutagen, reproductive
effector
Reproductive Toxicity:
Has shown teratogenic effects in laboratory animals.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
2-Butoxyethanol (111-76-2) No No None
12. Ecological Information
Environmental Fate:
When released into the soil, this material is not expected to evaporate
significantly. When released into the soil, this material may leach into
groundwater. When released into the soil, this material may biodegrade to a
moderate extent. When released into water, this material is not expected to
evaporate significantly. When released into water, this material may
biodegrade to a moderate extent. This material has an estimated
bioconcentration factor (BCF) of less than 100. This material is not
expected to significantly bioaccumulate. When released into the air, this
material is expected to be readily degraded by reaction with
photochemically produced hydroxyl radicals. When released into the air,
this material is expected to have a half-life of less than 1 day.
Environmental Toxicity:
The LC50/96-hour values for fish are over 100 mg/l. This material is not
expected to be toxic to aquatic life.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an
appropriate and approved waste disposal facility. Processing, use or
contamination of this product may change the waste management options.
State and local disposal regulations may differ from federal disposal
regulations.
Dispose of container and unused contents in accordance with federal, state
and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S. (ETHYLENE GLYCOL
MONOBUTYL ETHER)
Hazard Class: 6.1
UN/NA: UN2810
Packing Group: III
Information reported for product/size: 20L
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S. (ETHYLENE GLYCOL
MONOBUTYL ETHER)
Hazard Class: 6.1
UN/NA: UN2810
Packing Group: III
Information reported for product/size: 20L
International (Air, I.C.A.O.)
-----------------------------
Proper Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S. (ETHYLENE GLYCOL
MONOBUTYL ETHER)
Hazard Class: 6.1
UN/NA: UN2810
Packing Group: III
Information reported for product/size: 20L
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
2-Butoxyethanol (111-76-2) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
2-Butoxyethanol (111-76-2) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
2-Butoxyethanol (111-76-2) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
2-Butoxyethanol (111-76-2) No No Yes
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: Yes Pressure: No
Reactivity: No (Pure / Liquid)
Australian Hazchem Code: 2R
Poison Schedule: No information found.
WHMIS:
This MSDS has been prepared according to the hazard criteria of
the Controlled Products Regulations (CPR) and the MSDS contains
all of the information required by the CPR.
16. Other Information
NFPA Ratings:
Health: 2 Flammability: 2 Reactivity: 0
Label Hazard Warning:
WARNING! HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. CAUSES EYE
IRRITATION. AFFECTS CENTRAL NERVOUS SYSTEM, BLOOD AND BLOOD-FORMING ORGANS,
KIDNEYS, LIVER AND LYMPHOID SYSTEM. COMBUSTIBLE LIQUID AND VAPOR. MAY CAUSE
IRRITATION TO SKIN AND RESPIRATORY TRACT.
Label Precautions:
Avoid breathing vapor or mist.
Avoid contact with eyes, skin and clothing.
Keep container closed.
Use only with adequate ventilation.
Wash thoroughly after handling.
Keep away from heat and flame.
Label First Aid:
In all cases call a physician immediately. If swallowed, induce vomiting
immediately as directed by medical personnel. Never give anything by mouth to
an unconscious person. If inhaled, remove to fresh air. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. In case
of contact, immediately flush eyes or skin with plenty of water for at least
15 minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Product Use:
Laboratory Reagent.
Revision Information:
Pure. New 16 section MSDS format, all sections have been revised.
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in good
faith but makes no representation as to its comprehensiveness or accuracy. This
document is intended only as a guide to the appropriate precautionary handling
of the material by a properly trained person using this product. Individuals
receiving the information must exercise their independent judgment in
determining its appropriateness for a particular purpose. MALLINCKRODT BAKER,
INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED,
INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A
PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE
PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC.
WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS
INFORMATION.
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Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)