n-BUTYLAMINE

MSDS Number: B6340 --- Effective Date: 12/08/96


1. Product Identification

Synonyms: 1-Butanamine; 1-aminobutane; n-butylamine 96%
CAS No.: 109-73-9
Molecular Weight: 73.14
Chemical Formula: CH2(CH2)3NH2
Product Codes: J.T. Baker: D727 Mallinckrodt: 1822


2. Composition/Information on Ingredients


  Ingredient                                CAS No         Percent   Hazardous                                       
  ---------------------------------------   ------------   -------   ---------        
 
  Butylamine                                109-73-9         100%       Yes                                                               
 


3. Hazards Identification

Emergency Overview
--------------------------
DANGER! EXTREMELY FLAMMABLE LIQUID AND VAPOR. VAPOR MAY CAUSE FLASH FIRE. CORROSIVE. CAUSES BURNS TO ANY AREA OF CONTACT. HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. AFFECTS CENTRAL NERVOUS SYSTEM.


J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 2 - Moderate
Flammability Rating: 4 - Extreme (Flammable)
Reactivity Rating: 2 - Moderate
Contact Rating: 3 - Severe (Corrosive)
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER GLOVES; CLASS B EXTINGUISHER
Storage Color Code: Red (Flammable)
-----------------------------------------------------------------------------------------------------------

Potential Health Effects
----------------------------------

Inhalation:
Vapors can irritate the nose and throat and may produce headache and pulmonary edema. Exposure to excessive vapor concentrations may cause nausea, vomiting, faintness, coughing, chest pains, dizziness, depression, convulsions, narcosis and possibly unconsciousness. Exposure of this nature is unlikely, however, because of the irritating properties of the vapor.

Ingestion:
Toxic. Ingestion is harmful and symptoms may parallel those from inhalation. Can also cause irritation to the mouth, throat and gastro-intestinal tract. Ingestion can be fatal.

Skin Contact:
Contact may cause deep penetrating burns. Can be absorbed through the skin with symptoms paralleling those from inhalation.

Eye Contact:
Vapors irritate the eyes and splashes can cause burns, severe damage, and loss of vision.

Chronic Exposure:
Prolonged or repeated skin exposure may cause dermatitis.

Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders or eye problems or impaired respiratory function may be more susceptible to the effects of the substance.


4. First Aid Measures

Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician. Call a physician immediately.

Ingestion:
DO NOT INDUCE VOMITING. Give large quantities of water. Never give anything by mouth to an unconscious person. Call a physician immediately.

Skin Contact:
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before re-use. Thoroughly clean shoes before reuse. Call a physician immediately.

Eye Contact:
Immediately flush eyes with gentle but large stream of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Call a physician immediately.

Note to Physician:
For severe exposures, monitor for delayed onset of pulmonary edema.


5. Fire Fighting Measures

Fire:
Flash point: -12C (10F) CC Autoignition temperature: 312C (594F) Flammable limits in air % by volume: lel: 1.7; uel: 9.8 Extremely Flammable. Dangerous fire hazard when exposed to heat, flame, or oxidizers.

Explosion:
Above flash point, vapor-air mixtures are explosive within flammable limits noted above. Sensitive to static discharge.

Fire Extinguishing Media:
Dry chemical, alcohol foam or carbon dioxide. Do not use a solid stream of water, since the stream will scatter and spread the fire. Water spray may be used to keep fire exposed containers cool, dilute spills to nonflammable mixtures, protect personnel attempting to stop leak and disperse vapors.

Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. Vapors can flow along surfaces to distant ignition source and flash back. Closed containers exposed to heat may explode. Contact with strong oxidizers may cause fire.


6. Accidental Release Measures

Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel from entering. Contain and recover liquid when possible. Use non-sparking tools and equipment. Collect liquid in an appropriate container or absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a chemical waste container. Do not use combustible materials, such as saw dust. Do not flush to sewer! Use water spray to reduce vapors. US Regulations (CERCLA) require reporting spills and releases to soil, water and air in excess of reportable quantities. The toll free number for the US Coast Guard National Response Center is (800) 424-8802. J. T. Baker SOLUSORB(tm) solvent adsorbent is recommended for spills of this product.


7. Handling and Storage

Protect against physical damage. Store in a cool, dry well-ventilated location, away from any area where the fire hazard may be acute. Outside or detached storage is preferred. Separate from incompatibles. Containers should be bonded and grounded for transfers to avoid static sparks. Storage and use areas should be No Smoking areas. Use non-sparking type tools and equipment, including explosion proof ventilation. Containers of this material may be hazardous when empty since they retain product residues (vapors, liquid); observe all warnings and precautions listed for the product.


8. Exposure Controls/Personal Protection

Airborne Exposure Limits:
-OSHA Permissible Exposure Limit (PEL): 5 ppm Ceiling (skin). -ACGIH Threshold Limit Value (TLV): 5 ppm Ceiling (skin)

Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details. Use explosion-proof equipment.

Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded, a half-face respirator with an ammonia/methylamine cartridge may be worn for up to ten times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. A full-face piece respirator with an ammonia/methylamine cartridge may be worn up to 50 times the exposure limit, or the maximum use concentration specified by the appropriate regulatory agency, or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres. Not specifically approved, but better service life than organic vapor cartridge.

Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.

Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.


9. Physical and Chemical Properties

Appearance:
Clear, colorless liquid.

Odor:
Ammonia odor.

Solubility:
Miscible in water.

Specific Gravity:
0.740

pH:
No information found.

% Volatiles by volume @ 21C (70F):
100

Boiling Point:
78C (172F)

Melting Point:
-49C (-56F)

Vapor Density (Air=1):
2.5

Vapor Pressure (mm Hg):
82 @ 20C (68F)

Evaporation Rate (BuAc=1):
7.3


10. Stability and Reactivity

Stability:
Stable under ordinary conditions of use and storage.

Hazardous Decomposition Products:
Burning may produce carbon monoxide, carbon dioxide, nitrogen oxides.

Hazardous Polymerization:
Will not occur.

Incompatibilities:
Oxidizing agents, perchloryl fluoride and strong acids.

Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.


11. Toxicological Information


Oral rat LD50: 366 mg/kg; Skin rabbit LD50:500 mg/kg; Irritation skin rabbit, open Draize, 500 mg, severe; Investigated as a tumorigen, mutagen

  --------\Cancer Lists\------------------------------------------------------
                                         ---NTP Carcinogen---
  Ingredient                             Known    Anticipated    IARC Category
  ------------------------------------   -----    -----------    -------------
  Butylamine (109-73-9)                   No          No            None


12. Ecological Information

Environmental Fate:
When released into the soil, this material is expected to leach into groundwater. When released into the soil, this material may biodegrade to a moderate extent. When released into the soil, this material may evaporate to a moderate extent. When released into water, this material may biodegrade to a moderate extent. This material is not expected to significantly bioaccumulate. This material has an estimated bioconcentration factor (BCF) of less than 100. When released to water, this material is expected to quickly evaporate. When released into the water, this material is expected to have a half-life between 1 and 10 days. When released into the air, this material is expected to be readily degraded by reaction with photochemically produced hydroxyl radicals. When released into the air, this material is expected to have a half-life between 1 and 10 days. When released into the air, this material is expected to be readily removed from the atmosphere by wet deposition.

Environmental Toxicity:
No information found.


13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and sent to a RCRA approved waste facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.


14. Transport Information

Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: N-BUTYLAMINE
Hazard Class: 3, 8
UN/NA: UN1125
Packing Group: II
Information reported for product/size: 500ML

International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: NORMAL-BUTYLAMINE
Hazard Class: 3.2, 8
UN/NA: UN1125
Packing Group: II
Information reported for product/size: 500ML

International (Air, I.C.A.O.)
-----------------------------
Proper Shipping Name: NORMAL-BUTYLAMINE
Hazard Class: 3.2, 8
UN/NA: UN1125
Packing Group: II
Information reported for product/size: 500ML



15. Regulatory Information


  --------\Chemical Inventory Status - Part 1\---------------------------------
  Ingredient                                       TSCA  EC   Japan  Australia
  -----------------------------------------------  ----  ---  -----  ---------
  Butylamine (109-73-9)                             Yes  Yes   Yes      Yes                                      
 
  --------\Chemical Inventory Status - Part 2\---------------------------------
                                                          --Canada--
  Ingredient                                       Korea  DSL   NDSL  Phil.
  -----------------------------------------------  -----  ---   ----  -----
  Butylamine (109-73-9)                             Yes   Yes   No     Yes                             
 
  --------\Federal, State & International Regulations - Part 1\----------------
                                             -SARA 302-    ------SARA 313------
  Ingredient                                 RQ    TPQ     List  Chemical Catg.
  -----------------------------------------  ---   -----   ----  --------------
  Butylamine (109-73-9)                      No    No      No         No
 
  --------\Federal, State & International Regulations - Part 2\----------------
                                                        -RCRA-    -TSCA-
  Ingredient                                 CERCLA     261.33     8(d) 
  -----------------------------------------  ------     ------    ------
  Butylamine (109-73-9)                      1000       No         No                   
 
 
Chemical Weapons Convention:  No     TSCA 12(b):  No     CDTA:  No
SARA 311/312:  Acute: Yes      Chronic: Yes  Fire: Yes Pressure: No
Reactivity: No          (Pure / Liquid)


Australian Hazchem Code: 2WE
Poison Schedule: No information found.

WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.


16. Other Information

NFPA Ratings: Health: 2 Flammability: 3 Reactivity: 0

Label Hazard Warning:
DANGER! EXTREMELY FLAMMABLE LIQUID AND VAPOR. VAPOR MAY CAUSE FLASH FIRE. CORROSIVE. CAUSES BURNS TO ANY AREA OF CONTACT. HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. AFFECTS CENTRAL NERVOUS SYSTEM.

Label Precautions:
Do not breathe vapor. Do not get in eyes, on skin, or on clothing. Keep container closed. Use only with adequate ventilation. Wash thoroughly after handling. Keep away from heat, sparks and flame.

Label First Aid:
If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never give anything by mouth to an unconscious person. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. In all cases call a physician immediately.

Product Use:
Laboratory Reagent.

Revision Information:
Pure. New 16 section MSDS format, all sections have been revised.

Disclaimer:
************************************************************************************************ Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
************************************************************************************************ Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)