DICHLOROACETIC ACID

MSDS Number: D2144 --- Effective Date: 12/08/96


1. Product Identification

Synonyms: Acetic acid, dichloro-; DCA; bichloroacetic acid; dichloroethanoic acid
CAS No.: 79-43-6
Molecular Weight: 128.94
Chemical Formula: C2H2Cl2O2
Product Codes: J.T. Baker: G897 Mallinckrodt: V221


2. Composition/Information on Ingredients


  Ingredient                                CAS No         Percent   Hazardous                                       
  ---------------------------------------   ------------   -------   ---------        
 
  Dichloroacetic Acid                       79-43-6          100%       Yes                                                               
 


3. Hazards Identification

Emergency Overview
--------------------------
DANGER! CORROSIVE. CAUSES BURNS TO SKIN AND EYES. HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. INHALATION MAY BE FATAL AS A RESULT OF SPASM/INFLAMMATION OF THE RESPIRATORY TRACT.


J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 1 - Slight
Flammability Rating: 0 - None
Reactivity Rating: 1 - Slight
Contact Rating: 3 - Severe (Corrosive)
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES
Storage Color Code: White (Corrosive)
-----------------------------------------------------------------------------------------------------------

Potential Health Effects
----------------------------------

Information on the human health effects from exposure to this substance is limited.

Inhalation:
Corrosive. Extremely destructive to tissues of the mucous membranes and upper respiratory tract. Symptoms may include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea and vomiting. Inhalation may be fatal as a result of spasm inflammation and edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema.

Ingestion:
Extremely destructive to tissues.

Skin Contact:
Extremely destructive to skin.

Eye Contact:
Extremely destructive to eyes.

Chronic Exposure:
No information found.

Aggravation of Pre-existing Conditions:
No information found.


4. First Aid Measures

Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.

Ingestion:
If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never give anything by mouth to an unconscious person. Get medical attention immediately.

Skin Contact:
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention immediately.

Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.


5. Fire Fighting Measures

Fire:
Not considered to be a fire hazard.

Explosion:
Not considered to be an explosion hazard.

Fire Extinguishing Media:
Use any means suitable for extinguishing surrounding fire.

Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.


6. Accidental Release Measures

Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel from entering. Use water spray to dilute spill to a nonflammable mixture. Contain and recover liquid when possible. Collect liquid in an appropriate container or absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a chemical waste container. Use non-sparking tools and equipment. Do not use combustible materials, such as saw dust. Do not flush to sewer! J. T. Baker NEUTRASORB(tm) or TEAM(tm) 'Low Na+' acid neutralizers are recommended for spills of this product.


7. Handling and Storage

Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Isolate from incompatible substances. Containers of this material may be hazardous when empty since they retain product residues (vapors, liquid); observe all warnings and precautions listed for the product.


8. Exposure Controls/Personal Protection

Airborne Exposure Limits:
None established.

Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.

Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded, a half-face respirator with an acid gas cartridge may be worn for up to ten times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. A full-face piece respirator with an acid gas cartridge may be worn up to 50 times the exposure limit, or the maximum use concentration specified by the appropriate regulatory agency, or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.

Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.

Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.


9. Physical and Chemical Properties

Product may solidify at room temperature.
Appearance:
Clear, colorless liquid.

Odor:
Pungent odor.

Solubility:
Soluble in water.

Specific Gravity:
1.563

pH:
No information found.

% Volatiles by volume @ 21C (70F):
No information found.

Boiling Point:
194C (381F)

Melting Point:
9 - 11C (48 - 52F)

Vapor Density (Air=1):
4.5

Vapor Pressure (mm Hg):
1 @ 44C (111F)

Evaporation Rate (BuAc=1):
No information found.


10. Stability and Reactivity

Stability:
Stable under ordinary conditions of use and storage.

Hazardous Decomposition Products:
May emit oxides of carbon and hydrogen chloride gas when heated to decomposition.

Hazardous Polymerization:
Will not occur.

Incompatibilities:
Strong oxidizers, bases, and reducing agents.

Conditions to Avoid:
Heat and moisture.


11. Toxicological Information


Oral rat LD50: 2820 mg/kg Skin rabbit LD50: 510 mg/kg. Draize, skin, rabbit: 2mg/24hr severe. Draize, eye, rabbit: 50ug open severe. Investigated as a tumorigen, mutagen, reproductive effector.

  --------\Cancer Lists\------------------------------------------------------
                                         ---NTP Carcinogen---
  Ingredient                             Known    Anticipated    IARC Category
  ------------------------------------   -----    -----------    -------------
  Dichloroacetic Acid (79-43-6)           No          No              3


12. Ecological Information

Environmental Fate:
No information found.

Environmental Toxicity:
No information found.


13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste facility. Although not a listed RCRA hazardous waste, this material may exhibit one or more characteristics of a hazardous waste and require appropriate analysis to determine specific disposal requirements. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.


14. Transport Information

Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: DICHLOROACETIC ACID
Hazard Class: 8
UN/NA: UN1764
Packing Group: II
Information reported for product/size: 500ML

International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: DICHLOROACETIC ACID
Hazard Class: 8
UN/NA: UN1764
Packing Group: II
Information reported for product/size: 500ML

International (Air, I.C.A.O.)
-----------------------------
Proper Shipping Name: DICHLOROACETIC ACID
Hazard Class: 8
UN/NA: UN1764
Packing Group: II
Information reported for product/size: 500ML



15. Regulatory Information


  --------\Chemical Inventory Status - Part 1\---------------------------------
  Ingredient                                       TSCA  EC   Japan  Australia
  -----------------------------------------------  ----  ---  -----  ---------
  Dichloroacetic Acid (79-43-6)                     Yes  Yes   Yes      Yes                                      
 
  --------\Chemical Inventory Status - Part 2\---------------------------------
                                                          --Canada--
  Ingredient                                       Korea  DSL   NDSL  Phil.
  -----------------------------------------------  -----  ---   ----  -----
  Dichloroacetic Acid (79-43-6)                     Yes   Yes   No     Yes                             
 
  --------\Federal, State & International Regulations - Part 1\----------------
                                             -SARA 302-    ------SARA 313------
  Ingredient                                 RQ    TPQ     List  Chemical Catg.
  -----------------------------------------  ---   -----   ----  --------------
  Dichloroacetic Acid (79-43-6)              No    No      No         No
 
  --------\Federal, State & International Regulations - Part 2\----------------
                                                        -RCRA-    -TSCA-
  Ingredient                                 CERCLA     261.33     8(d) 
  -----------------------------------------  ------     ------    ------
  Dichloroacetic Acid (79-43-6)              No         No         No                   
 
 
Chemical Weapons Convention:  No     TSCA 12(b):  No     CDTA:  No
SARA 311/312:  Acute: Yes      Chronic: No   Fire: No  Pressure: No
Reactivity: No          (Pure / Liquid)
Prop 65:
THIS PRODUCT CONTAINS A CHEMICAL(S) KNOWN TO THE STATE OF CALIFORNIA TO CAUSE CANCER.

Australian Hazchem Code: 2R
Poison Schedule: No information found.

WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.


16. Other Information

NFPA Ratings: Health: 3 Flammability: 1 Reactivity: 0

Label Hazard Warning:
DANGER! CORROSIVE. CAUSES BURNS TO SKIN AND EYES. HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. INHALATION MAY BE FATAL AS A RESULT OF SPASM/INFLAMMATION OF THE RESPIRATORY TRACT.

Label Precautions:
Do not breathe vapor. Do not get in eyes, on skin, or on clothing. Keep container closed. Use only with adequate ventilation. Wash thoroughly after handling.

Label First Aid:
In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never give anything by mouth to an unconscious person. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. In all cases get medical attention immediately.

Product Use:
Laboratory Reagent.

Revision Information:
Pure. New 16 section MSDS format, all sections have been revised.

Disclaimer:
************************************************************************************************ Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
************************************************************************************************ Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)