IMIDAZOLE
MSDS Number: I0080 --- Effective Date: 09/08/97
1. Product Identification
Synonyms: Glyoxaline; Iminazole
CAS No.: 288-32-4
Molecular Weight: 68
Chemical Formula: C3H4N2
Product Codes:
J.T. Baker:
N811
Mallinckrodt:
4337
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Imidazole 288-32-4 90 - 100% Yes
3. Hazards Identification
Emergency Overview
--------------------------
WARNING! CAUSES IRRITATION TO EYES AND SKIN. MAY BE HARMFUL IF
SWALLOWED, INHALED OR ABSORBED THROUGH SKIN.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 2 - Moderate
Flammability Rating: 1 - Slight
Reactivity Rating: 1 - Slight
Contact Rating: 3 - Severe (Corrosive)
Lab Protective Equip: GOGGLES; LAB COAT
Storage Color Code: White (Corrosive)
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Potential Health Effects
----------------------------------
Information on the human health effects from exposure to this substance is
limited.
Inhalation:
May cause irritation to the respiratory tract. Symptoms may include
coughing and shortness of breath.
Ingestion:
Large oral doses may cause irritation to the gastrointestinal tract.
Skin Contact:
Causes irritation to skin. Symptoms include redness, itching, and pain. May
be absorbed through the skin with possible systemic effects.
Eye Contact:
Causes irritation, redness, and pain.
Chronic Exposure:
No information found.
Aggravation of Pre-existing Conditions:
No information found.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical attention.
Ingestion:
Give large amounts of water to drink. Never give anything by mouth to an
unconscious person. Get medical attention.
Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes. Remove
contaminated clothing and shoes. Get medical attention. Wash clothing
before reuse. Thoroughly clean shoes before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes,
lifting lower and upper eyelids occasionally. Get medical attention
immediately.
5. Fire Fighting Measures
Fire:
As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition source.
Explosion:
Fine dust dispersed in air in sufficient concentrations, and in the
presence of an ignition source is a potential dust explosion hazard.
Fire Extinguishing Media:
Water spray, dry chemical, alcohol foam, or carbon dioxide.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved
self-contained breathing apparatus with full facepiece operated in the
pressure demand or other positive pressure mode.
6. Accidental Release Measures
Remove all sources of ignition. Ventilate area of leak or spill. Wear
appropriate personal protective equipment as specified in Section 8.
Spills: Clean up spills in a manner that does not disperse dust into the
air. Use non-sparking tools and equipment. Reduce airborne dust and prevent
scattering by moistening with water. Pick up spill for recovery or disposal
and place in a closed container.
7. Handling and Storage
Keep in a tightly closed container, stored in a cool, dry, ventilated area.
Protect against physical damage. Containers of this material may be
hazardous when empty since they retain product residues (dust, solids);
observe all warnings and precautions listed for the product. Isolate from
incompatible substances.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
- OSHA Permissible Exposure Limit (PEL):
15 mg/m3 total dust, 5 mg/m3 respirable fraction for nuisance dusts.
- ACGIH Threshold Limit Value (TLV):
10 mg/m3 total dust containing no asbestos and < 1% crystalline silica for Particulates Not Otherwise Classified (PNOC).
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee
exposures below the Airborne
Exposure Limits. Local exhaust ventilation is generally preferred because
it can control the emissions of the contaminant at its source, preventing
dispersion of it into the general work area. Please refer to the ACGIH
document, Industrial Ventilation, A Manual of Recommended Practices,
most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded, a half-face dust/mist respirator may be
worn for up to ten times the exposure limit or the maximum use
concentration specified by the appropriate regulatory agency or respirator
supplier, whichever is lowest. A full-face piece dust/mist respirator may
be worn up to 50 times the exposure limit, or the maximum use concentration
specified by the appropriate regulatory agency, or respirator supplier,
whichever is lowest. For emergencies or instances where the exposure
levels are not known, use a full-facepiece positive-pressure, air-supplied
respirator. WARNING: Air-purifying respirators do not protect workers in
oxygen-deficient atmospheres.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat,
apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles. Maintain eye wash fountain and quick-drench
facilities in work area.
9. Physical and Chemical Properties
Appearance:
White flakes.
Odor:
No information found.
Solubility:
Soluble in water.
Specific Gravity:
0.60
pH:
No information found.
% Volatiles by volume @ 21C (70F):
0
Boiling Point:
256C (493F)
Melting Point:
89 - 91C (192 - 196F)
Vapor Density (Air=1):
No information found.
Vapor Pressure (mm Hg):
No information found.
Evaporation Rate (BuAc=1):
No information found.
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Burning may produce carbon monoxide, carbon dioxide, nitrogen oxides.
Hazardous Polymerization:
This substance does not polymerize.
Incompatibilities:
Strong oxidizers.
Conditions to Avoid:
No information found.
11. Toxicological Information
Oral rat LD50: 220 mg/Kg. Investigated as a mutagen, reproductive effector.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Imidazole (288-32-4) No No None
12. Ecological Information
Environmental Fate:
No information found.
Environmental Toxicity:
No information found.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an
appropriate and approved waste disposal facility. Processing, use or
contamination of this product may change the waste management options.
State and local disposal regulations may differ from federal disposal
regulations.
Dispose of container and unused contents in accordance with federal, state
and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: CORROSIVE SOLID, BASIC, ORGANIC, N.O.S.
(IMIDAZOLE)
Hazard Class: 8
UN/NA: UN3263
Packing Group: III
Information reported for product/size: 5KG
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: CORROSIVE SOLID, BASIC, ORGANIC, N.O.S.
(IMIDAZOLE)
Hazard Class: 8
UN/NA: UN3263
Packing Group: III
Information reported for product/size: 5KG
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Imidazole (288-32-4) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Imidazole (288-32-4) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Imidazole (288-32-4) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Imidazole (288-32-4) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: No Fire: No Pressure: No
Reactivity: No (Pure / Solid)
Australian Hazchem Code: No information found.
Poison Schedule: No information found.
WHMIS:
This MSDS has been prepared according to the hazard criteria of
the Controlled Products Regulations (CPR) and the MSDS contains
all of the information required by the CPR.
16. Other Information
NFPA Ratings:
Health: 1 Flammability: 1 Reactivity: 0
Label Hazard Warning:
WARNING! CAUSES IRRITATION TO EYES AND SKIN. MAY BE HARMFUL IF SWALLOWED,
INHALED OR ABSORBED THROUGH SKIN.
Label Precautions:
Avoid contact with eyes, skin and clothing.
Wash thoroughly after handling.
Avoid breathing dust.
Use with adequate ventilation.
Keep container closed.
Label First Aid:
In case of contact, immediately flush eyes or skin with plenty of water for
at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing
before reuse. If inhaled, remove to fresh air. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. If swallowed,
give large amounts of water to drink. Never give anything by mouth to an
unconscious person. In all cases, get medical attention.
Product Use:
Laboratory Reagent.
Revision Information:
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in
good faith but makes no representation as to its comprehensiveness or accuracy.
This document is intended only as a guide to the appropriate precautionary
handling of the material by a properly trained person using this product.
Individuals receiving the information must exercise their independent judgment
in determining its appropriateness for a particular purpose. MALLINCKRODT
BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED,
INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A
PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE
PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC.
WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS
INFORMATION.
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Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)