INDIGO CARMINE

MSDS Number: I1440 --- Effective Date: 12/08/96


1. Product Identification

Synonyms: Indigo carmine, indicator grade; Acid blue W; CI 73015
CAS No.: 860-22-0
Molecular Weight: 466.36
Chemical Formula: C16H10N2O8S2.2Na
Product Codes: J.T. Baker: N877 Mallinckrodt: 2489


2. Composition/Information on Ingredients


  Ingredient                                CAS No         Percent   Hazardous                                       
  ---------------------------------------   ------------   -------   ---------        
 
  Indigo Carmine                            860-22-0       90 - 100%    Yes                                                                  
 


3. Hazards Identification

Emergency Overview
--------------------------
CAUTION! MAY BE HARMFUL IF SWALLOWED.


J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 2 - Moderate
Flammability Rating: 1 - Slight
Reactivity Rating: 0 - None
Contact Rating: 2 - Moderate
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES
Storage Color Code: Orange (General Storage)
-----------------------------------------------------------------------------------------------------------

Potential Health Effects
----------------------------------

Inhalation:
No adverse health effects expected from inhalation.

Ingestion:
Low level of toxicity by ingestion. May cause irritation to the gastrointestinal tract. Symptoms may include nausea, vomiting and diarrhea.

Skin Contact:
No adverse effects expected.

Eye Contact:
No adverse effects expected.

Chronic Exposure:
No information found.

Aggravation of Pre-existing Conditions:
No information found.


4. First Aid Measures

Inhalation:
Not expected to require first aid measures. Remove to fresh air. Get medical attention for any breathing difficulty.

Ingestion:
If swallowed, give several glasses of water to drink to dilute. If large amounts were swallowed or symptoms occur, get medical advice. Never give anything by mouth to an unconscious person.

Skin Contact:
Wash exposed area with soap and water. Get medical advice if irritation develops.

Eye Contact:
Wash thoroughly with running water. Get medical advice if irritation develops.


5. Fire Fighting Measures

Fire:
Not considered to be a fire hazard.

Explosion:
Not considered to be an explosion hazard.

Fire Extinguishing Media:
Use any means suitable for extinguishing surrounding fire.

Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.


6. Accidental Release Measures

Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Spills: Sweep up and containerize for reclamation or disposal. Vacuuming or wet sweeping may be used to avoid dust dispersal.


7. Handling and Storage

Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Protect from light. Protect from freezing. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product.


8. Exposure Controls/Personal Protection

Airborne Exposure Limits:
None established.

Ventilation System:
Not expected to require any special ventilation.

Personal Respirators (NIOSH Approved):
Not expected to require personal respirator usage.

Skin Protection:
Wear protective gloves and clean body-covering clothing.

Eye Protection:
Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.


9. Physical and Chemical Properties

Appearance:
Dark purple powder.

Odor:
Light odor.

Solubility:
1 gm/100 ml water.

Specific Gravity:
No information found.

pH:
No information found.

% Volatiles by volume @ 21C (70F):
0

Boiling Point:
No information found.

Melting Point:
> 300C (> 572F)

Vapor Density (Air=1):
No information found.

Vapor Pressure (mm Hg):
No information found.

Evaporation Rate (BuAc=1):
No information found.


10. Stability and Reactivity

Stability:
Stable under ordinary conditions of use and storage. Light sensitive.

Hazardous Decomposition Products:
Burning may produce carbon monoxide, carbon dioxide, sulfur oxides, and nitrogen oxides.

Hazardous Polymerization:
Will not occur.

Incompatibilities:
Strong oxidizing agents.

Conditions to Avoid:
Light and incompatibles.


11. Toxicological Information


Oral rat LD50: 2000 mg/Kg. Investigated as a tumorigen and mutagen.

  --------\Cancer Lists\------------------------------------------------------
                                         ---NTP Carcinogen---
  Ingredient                             Known    Anticipated    IARC Category
  ------------------------------------   -----    -----------    -------------
  Indigo Carmine (860-22-0)               No          No            None


12. Ecological Information

Environmental Fate:
No information found.

Environmental Toxicity:
No information found.


13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.


14. Transport Information

Not regulated.


15. Regulatory Information


  --------\Chemical Inventory Status - Part 1\---------------------------------
  Ingredient                                       TSCA  EC   Japan  Australia
  -----------------------------------------------  ----  ---  -----  ---------
  Indigo Carmine (860-22-0)                         Yes  Yes   Yes      Yes                                      
 
  --------\Chemical Inventory Status - Part 2\---------------------------------
                                                          --Canada--
  Ingredient                                       Korea  DSL   NDSL  Phil.
  -----------------------------------------------  -----  ---   ----  -----
  Indigo Carmine (860-22-0)                         Yes   Yes   No     Yes                             
 
  --------\Federal, State & International Regulations - Part 1\----------------
                                             -SARA 302-    ------SARA 313------
  Ingredient                                 RQ    TPQ     List  Chemical Catg.
  -----------------------------------------  ---   -----   ----  --------------
  Indigo Carmine (860-22-0)                  No    No      No         No
 
  --------\Federal, State & International Regulations - Part 2\----------------
                                                        -RCRA-    -TSCA-
  Ingredient                                 CERCLA     261.33     8(d) 
  -----------------------------------------  ------     ------    ------
  Indigo Carmine (860-22-0)                  No         No         No                   
 
 
Chemical Weapons Convention:  No     TSCA 12(b):  No     CDTA:  No
SARA 311/312:  Acute: Yes      Chronic: No   Fire: No  Pressure: No
Reactivity: No          (Pure / Solid) 


Australian Hazchem Code: No information found.
Poison Schedule: No information found.

WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.


16. Other Information

NFPA Ratings: Health: 1 Flammability: 0 Reactivity: 0

Label Hazard Warning:
CAUTION! MAY BE HARMFUL IF SWALLOWED.

Label Precautions:
Wash thoroughly after handling.

Label First Aid:
If swallowed, give several glasses of water to drink to dilute. If large amounts were swallowed or symptoms occur, get medical advice. Never give anything by mouth to an unconscious person.

Product Use:
Laboratory Reagent.

Revision Information:
Pure. New 16 section MSDS format, all sections have been revised.

Disclaimer:
************************************************************************************************ Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
************************************************************************************************ Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)