MALEIC ACID

MSDS Number: M0325 --- Effective Date: 12/08/96


1. Product Identification

Synonyms: (Z)-Butenedioic acid; cis-butenedioic acid; maleinic acid, toxilic acid
CAS No.: 110-16-7
Molecular Weight: 116.08
Chemical Formula: HOOCCH=CHOOH
Product Codes: J.T. Baker: P460 Mallinckrodt: 1900


2. Composition/Information on Ingredients


  Ingredient                                CAS No         Percent   Hazardous                                       
  ---------------------------------------   ------------   -------   ---------        
 
  Maleic Acid                               110-16-7         100%       Yes                                                               
 


3. Hazards Identification

Emergency Overview
--------------------------
WARNING! CORROSIVE. CAUSES EYE BURNS. CAUSES IRRITATION TO SKIN AND RESPIRATORY TRACT. MAY BE HARMFUL IF SWALLOWED OR ABSORBED THROUGH SKIN.


J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 2 - Moderate
Flammability Rating: 1 - Slight
Reactivity Rating: 1 - Slight
Contact Rating: 2 - Moderate
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES
Storage Color Code: Orange (General Storage)
-----------------------------------------------------------------------------------------------------------

Potential Health Effects
----------------------------------

Inhalation:
Inhalation of dust is irritating to the mucous membrane and upper respiratory tract. May cause coughing, sore throat, shortness of breath.

Ingestion:
Harmful if swallowed. Causes sore throat, abdominal pain, vomiting.

Skin Contact:
Causes irritation. May be absorbed through skin.

Eye Contact:
Causes severe eye irritation with redness, and pain. Can cause eye burns and permanent damage.

Chronic Exposure:
No information found.

Aggravation of Pre-existing Conditions:
No information found.


4. First Aid Measures

Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.

Ingestion:
Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention.

Skin Contact:
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Call a physician.

Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.


5. Fire Fighting Measures

Fire:
As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition source.

Explosion:
Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.

Fire Extinguishing Media:
Water spray, dry chemical, alcohol foam, or carbon dioxide.

Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.


6. Accidental Release Measures

Remove all sources of ignition. Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Spills: Clean up spills in a manner that does not disperse dust into the air. Use non-sparking tools and equipment. Reduce airborne dust and prevent scattering by moistening with water. Pick up spill for recovery or disposal and place in a closed container. US Regulations (CERCLA) require reporting spills and releases to soil, water and air in excess of reportable quantities. The toll free number for the US Coast Guard National Response Center is (800) 424-8802.


7. Handling and Storage

Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Isolate from incompatible substances. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product. Avoid dust formation and control ignition sources. Employ grounding, venting and explosion relief provisions in accord with accepted engineering practices in any process capable of generating dust and/or static electricity. Empty only into inert or non-flammable atmosphere. Emptying contents into a non-inert atmosphere where flammable vapors may be present could cause a flash fire or explosion due to electrostatic discharge.


8. Exposure Controls/Personal Protection

Airborne Exposure Limits:
None established.

Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.

Personal Respirators (NIOSH Approved):
For conditions of use where exposure to the dust or mist is apparent, a half-face dust/mist respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.

Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.

Eye Protection:
Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.


9. Physical and Chemical Properties

Appearance:
White crystals.

Odor:
Faint acidulous odor.

Solubility:
79 g/100ml of water @ 25C (77F) Freely soluble.

Density:
1.590 @ 20C/4C

pH:
No information found.

% Volatiles by volume @ 21C (70F):
0

Boiling Point:
135C (275F) Decomposes.

Melting Point:
130C (266F)

Vapor Density (Air=1):
4.0

Vapor Pressure (mm Hg):
No information found.

Evaporation Rate (BuAc=1):
No information found.


10. Stability and Reactivity

Stability:
Stable under ordinary conditions of use and storage.

Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.

Hazardous Polymerization:
Will not occur.

Incompatibilities:
Strong oxidizers.

Conditions to Avoid:
Heat, dusting and incompatibles.


11. Toxicological Information


Oral rat LD50: 708 mg/Kg Skin rabbit LD50: 1560 mg/Kg Investigated as a mutagen.

  --------\Cancer Lists\------------------------------------------------------
                                         ---NTP Carcinogen---
  Ingredient                             Known    Anticipated    IARC Category
  ------------------------------------   -----    -----------    -------------
  Maleic Acid (110-16-7)                  No          No            None


12. Ecological Information

Environmental Fate:
When released into the soil, this material is expected to leach into groundwater. When released into the soil, this material is expected to readily biodegrade. When released into water, this material is expected to readily biodegrade. When released into water, this material is not expected to evaporate significantly. When released into the air, this material is expected to exist in the aerosol phase with a short half-life. When released into the air, this material is not expected to be subject to wet deposition. When released into the air, this material is expected to be degraded by reaction with ozone and photochemically produced hydroxyl radicals. This material is not expected to significantly bioaccumulate. This material has an estimated bioconcentration factor (BCF) of less than 100.

Environmental Toxicity:
TLm /Fathead minnow/5ppm/96 hr./fresh water TLm/Mosquito fish/240 ppm/24-48 hr./fresh water


13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.


14. Transport Information

Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: MALEIC ACID
Hazard Class: 8
UN/NA: NA2215
Packing Group: III
Information reported for product/size: 12KG

International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (MALEIC ACID)
Hazard Class: 8
UN/NA: UN3261
Packing Group: III
Information reported for product/size: 12KG

International (Air, I.C.A.O.)
-----------------------------
Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (MALEIC ACID)
Hazard Class: 8
UN/NA: UN3261
Packing Group: III
Information reported for product/size: 12KG



15. Regulatory Information


  --------\Chemical Inventory Status - Part 1\---------------------------------
  Ingredient                                       TSCA  EC   Japan  Australia
  -----------------------------------------------  ----  ---  -----  ---------
  Maleic Acid (110-16-7)                            Yes  Yes   Yes      Yes                                      
 
  --------\Chemical Inventory Status - Part 2\---------------------------------
                                                          --Canada--
  Ingredient                                       Korea  DSL   NDSL  Phil.
  -----------------------------------------------  -----  ---   ----  -----
  Maleic Acid (110-16-7)                            Yes   Yes   No     Yes                             
 
  --------\Federal, State & International Regulations - Part 1\----------------
                                             -SARA 302-    ------SARA 313------
  Ingredient                                 RQ    TPQ     List  Chemical Catg.
  -----------------------------------------  ---   -----   ----  --------------
  Maleic Acid (110-16-7)                     No    No      No         No
 
  --------\Federal, State & International Regulations - Part 2\----------------
                                                        -RCRA-    -TSCA-
  Ingredient                                 CERCLA     261.33     8(d) 
  -----------------------------------------  ------     ------    ------
  Maleic Acid (110-16-7)                     5000       No         No                   
 
 
Chemical Weapons Convention:  No     TSCA 12(b):  No     CDTA:  No
SARA 311/312:  Acute: Yes      Chronic: No   Fire: No  Pressure: No
Reactivity: No          (Pure / Solid) 


Australian Hazchem Code: No information found.
Poison Schedule: No information found.

WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.


16. Other Information

NFPA Ratings: Health: 3 Flammability: 1 Reactivity: 0

Label Hazard Warning:
WARNING! CORROSIVE. CAUSES EYE BURNS. CAUSES IRRITATION TO SKIN AND RESPIRATORY TRACT. MAY BE HARMFUL IF SWALLOWED OR ABSORBED THROUGH SKIN.

Label Precautions:
Do not breathe dust. Do not get in eyes, on skin, or on clothing. Keep container closed. Use only with adequate ventilation. Wash thoroughly after handling.

Label First Aid:
In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. Call a physician immediately. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician. If swallowed, call a physician immediately.

Product Use:
Laboratory Reagent.

Revision Information:
Pure. New 16 section MSDS format, all sections have been revised.

Disclaimer:
************************************************************************************************ Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
************************************************************************************************ Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)