PHENOL, CRYSTALS
MSDS Number: P1949 --- Effective Date: 09/08/97
1. Product Identification
Synonyms: Carbolic acid; Phenic acid; Phenylic acid; Hydroxybenzene;
Phenol, fused; Monohydroxybenzene; Phenol, solid
CAS No.: 108-95-2
Molecular Weight: 94.11
Chemical Formula: C6H5OH
Product Codes:
J.T. Baker:
2858, 2862, 4056
Mallinckrodt:
0028, 0052, 0273, 0605, H602
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Phenol 108-95-2 99 - 100% Yes
3. Hazards Identification
Emergency Overview
--------------------------
POISON! DANGER! MAY BE FATAL IF SWALLOWED, INHALED OR ABSORBED THROUGH
SKIN. RAPIDLY ABSORBED THROUGH SKIN. CORROSIVE. CAUSES SEVERE BURNS TO
EVERY AREA OF CONTACT. AFFECTS CENTRAL NERVOUS SYSTEM, LIVER AND KIDNEYS.
COMBUSTIBLE.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
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Health Rating: 3 - Severe (Life)
Flammability Rating: 2 - Moderate
Reactivity Rating: 1 - Slight
Contact Rating: 4 - Extreme (Corrosive)
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER
GLOVES; CLASS B EXTINGUISHER
Storage Color Code: Red Stripe (Store Separately)
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Potential Health Effects
----------------------------------
The major hazard of phenol is its ability to penetrate the skin rapidly,
particularly when liquid, causing severe injury which can be fatal. Phenol
also has a strong corrosive effect on body tissue causing severe chemical
burns. Due to its local anesthetizing properties, skin burns may be
painless.
Inhalation:
Breathing vapor, dust or mist results in digestive disturbances (vomiting,
difficulty in swallowing, diarrhea, loss of appetite). Will irritate,
possibly burn respiratory tract. Other symptoms listed under ingestion may
also occur.
Ingestion:
Poison. Symptoms may include burning pain in mouth and throat, abdominal
pain, nausea, vomiting, headache, dizziness, muscular weakness, central
nervous system effects, increase in heart rate, irregular breathing, coma,
and possibly death. Acute exposure is also associated with kidney and liver
damage. Ingestion of 1 gram has been lethal to humans.
Skin Contact:
Corrosive. Rapidly absorbed through the skin with systemic poisoning
effects to follow. Discoloration and severe burns may occur, but may be
disguised by a loss in pain sensation.
Eye Contact:
Corrosive. Eye burns with redness, pain, blurred vision may occur. May
cause severe damage and blindness.
Chronic Exposure:
Repeated exposure may cause symptoms described for acute poisoning as well
as eye and skin discoloration.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin, eye or central nervous system disorders, or
impaired liver, kidney, or pulmonary function may be more susceptible to
the effects of this substance.
4. First Aid Measures
IN CASE OF PHENOL POISONING, start first aid treatment immediately, then
get medical attention. People administering first aid should take
precautions to avoid contact with phenol. A phenol antidote kit (castor oil
or other vegetable oil, polyethylene glycol 300) should be available in any
phenol work area. Actions to be taken in case of phenol poisoning should be
planned and practiced before beginning work with phenol. Castor oil and or
polyethylene glycol can be given by a first responder before medical help
arrives.
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical attention immediately.
Ingestion:
If swallowed, immediately administer castor oil or other vegetable oil.
Never give anything by mouth to an unconscious person. Be ready to induce
vomiting at the advice of physician or poison control center. Castor oil
(or vegetable oil) dosage should be between 15 and 30 cc. Get medical
attention immediately.
Skin Contact:
In case of skin contact, immediately flush skin with large amounts of water
while removing contaminated clothing and shoes. As soon as possible,
repeatedly apply polyethylene glycol to affected area. Destroy contaminated
clothing and shoes. Flush skin with water for at least 30 minutes. It is
very important to avoid rubbing or wiping affected parts which would
aggravate irritation and cause product dispersion. Continue treatment until
the burned area changes color from white to pink. Expect that this can take
a long period of time (20 minutes or more). The polyethylene glycol
application should be done during transportation to the hospital. If
polyethylene glycol is not available, flush with water for at least 30
minutes prior to going to hospital. Get medical attention immediately.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes,
lifting lower and upper eyelids occasionally. Get medical attention
immediately.
Note to Physician:
Treat ingestion with gastric lavage using 40% aqueous Bacto-Peptone, milk
or water until phenolic odor is eliminated. Then give 15 to 50 cc castor or
vegetable oil. Debride necrotic skin. Monitor vital signs, fluid status,
electrolytes, BUN, renal and hepatic function, and electrocardiogram.
Manage sedation, seizures, renal failure, and fluid electrolyte imbalances
symptomatically as indicated.
5. Fire Fighting Measures
Fire:
Flash point: 79C (174F) CC
Autoignition temperature: 715C (1319F)
Flammable limits in air % by volume:
lel: 1.3; uel: 8.6
Combustible. Contact with strong oxidizers may cause fire.
Explosion:
Above flash point, vapor-air mixtures are explosive within flammable limits
noted above. Sealed containers may rupture when heated.
Fire Extinguishing Media:
Water spray, dry chemical, alcohol foam, or carbon dioxide. Water spray may
be used to keep fire exposed containers cool.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved
self-contained breathing apparatus with full facepiece operated in the
pressure demand or other positive pressure mode. Structural firefighter's
protective clothing is ineffective for fires involving this material. Stay
away from sealed containers.
6. Accidental Release Measures
Remove all sources of ignition. Ventilate area of leak or spill. Wear
appropriate personal protective equipment as specified in Section 8.
Spills: Clean up spills in a manner that does not disperse dust into the
air. Use non-sparking tools and equipment. Reduce airborne dust and prevent
scattering by moistening with water. Pick up spill for recovery or disposal
and place in a closed container. Do not flush to the sewer. Dry lime or
soda ash may be used on spill for neutralization. US Regulations (CERCLA)
require reporting spills and releases to soil, water and air in excess of
reportable quantities. The toll free number for the US Coast Guard National
Response Center is (800) 424-8802.
7. Handling and Storage
Keep in a tightly closed container. Store in a cool, dry, ventilated area
away from sources of heat or ignition. Protect against physical damage.
Store separately from reactive or combustible materials, and out of direct
sunlight. Avoid dust formation and control ignition sources. Employ
grounding, venting and explosion relief provisions in accord with accepted
engineering practices in any process capable of generating dust and/or
static electricity. Empty only into inert or non-flammable atmosphere.
Emptying contents into a non-inert atmosphere where flammable vapors may be
present could cause a flash fire or explosion due to electrostatic
discharge. All phenol workers should be properly trained on its hazards and
the proper protective measures required. This training should also include
emergency actions. All phenol operations should be enclosed to eliminate
any potential exposure routes. Containers of this material may be hazardous
when empty since they retain product residues (dust, solids); observe all
warnings and precautions listed for the product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
Phenol:
-OSHA Permissible Exposure Limit (PEL):
5 ppm (TWA) (skin)
-ACGIH Threshold Limit Value (TLV):
5 ppm (TWA) (skin)
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee
exposures below the Airborne
Exposure Limits. Local exhaust ventilation is generally preferred because
it can control the emissions of the contaminant at its source, preventing
dispersion of it into the general work area. Please refer to the ACGIH
document, Industrial Ventilation, A Manual of Recommended Practices,
most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded, a full facepiece respirator with organic
vapor cartridge and dust/mist filter may be worn up to 50 times the
exposure limit or the maximum use concentration specified by the
appropriate regulatory agency or respirator supplier, whichever is lowest.
For emergencies or instances where the exposure levels are not known, use a
full-facepiece positive-pressure, air-supplied respirator. WARNING: Air
purifying respirators do not protect workers in oxygen-deficient
atmospheres.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat,
apron or coveralls, as appropriate, to prevent skin contact. Butyl rubber
and neoprene are suitable materials for personal protective equipment.
Eye Protection:
Use chemical safety goggles and/or full face shield where dusting or
splashing of solutions is possible. Maintain eye wash fountain and
quick-drench facilities in work area.
9. Physical and Chemical Properties
Appearance:
Colorless to light pink crystals.
Odor:
Sharp, medicinal, sweet, tarry.
Solubility:
1 g/15 ml of water; very soluble in alcohol.
Specific Gravity:
1.06 @ 20C/4C
pH:
No information found.
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
182C (360F)
Melting Point:
43C (109F)
Vapor Density (Air=1):
3.2
Vapor Pressure (mm Hg):
0.4 @ 20C (68F)
Evaporation Rate (BuAc=1):
< 0.01
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage. Heat will contribute
to instability.
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Toxic gases and vapors may be released if involved in a fire.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Oxidizers, aluminum chloride and nitrobenzene, calcium hypochlorite,
butadiene, halogens, formaldehyde, mineral oxidizing acids, isocyanates,
sodium nitrite and many other materials. Hot liquid phenol will attack
aluminum, magnesium, lead, and zinc metals.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.
11. Toxicological Information
Oral rat LD50: 317 mg/Kg; skin rabbit LD50:630 mg/kg; inhalation rat LC50:
316 mg/m3; irritation data: skin rabbit, standard Draize, 500 mg/24H
severe; eye rabbit, standard Draize 5 mg/30S rinse, mild. Investigated as a
tumorigen, mutagen, reproductive effector.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Phenol (108-95-2) No No 3
12. Ecological Information
Environmental Fate:
When released into the soil, this material is expected to readily
biodegrade. When released into the soil, this material is not expected to
leach into groundwater. When released into the soil, this material may
evaporate to a moderate extent. When released into the soil, this material
is expected to have a half-life between 1 and 10 days. When released into
water, this material is expected to readily biodegrade. When released into
water, this material is not expected to evaporate significantly. When
released into water, this material is expected to have a half-life between
10 and 30 days. This material has an estimated bioconcentration factor
(BCF) of less than 100. This material is not expected to significantly
bioaccumulate. When released into the air, this material is expected to be
readily degraded by reaction with photochemically produced hydroxyl
radicals. When released into the air, this material may be moderately
degraded by photolysis. When released into the air, this material is
expected to have a half-life of less than 1 day.
Environmental Toxicity:
This material is expected to be toxic to aquatic life. The LC50/96-hour
values for fish are between 10 and 100 mg/l.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be handled as
hazardous waste and sent to a RCRA approved incinerator or disposed in a
RCRA approved waste facility. Processing, use or contamination of this
product may change the waste management options. State and local disposal
regulations may differ from federal disposal regulations.
Dispose of container and unused contents in accordance with federal, state
and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: PHENOL, SOLID
Hazard Class: 6.1
UN/NA: UN1671
Packing Group: II
Information reported for product/size: 2KG
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: PHENOL, SOLID
Hazard Class: 6.1
UN/NA: UN1671
Packing Group: II
Information reported for product/size: 2KG
International (Air, I.C.A.O.)
-----------------------------
Proper Shipping Name: PHENOL, SOLID
Hazard Class: 6.1
UN/NA: UN1671
Packing Group: II
Information reported for product/size: 2KG
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Phenol (108-95-2) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Phenol (108-95-2) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Phenol (108-95-2) 1000 500* Yes No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Phenol (108-95-2) 1000 U188 No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: Yes Pressure: No
Reactivity: No (Pure / Solid)
Australian Hazchem Code: 2X
Poison Schedule: S6
WHMIS:
This MSDS has been prepared according to the hazard criteria of
the Controlled Products Regulations (CPR) and the MSDS contains
all of the information required by the CPR.
16. Other Information
NFPA Ratings:
Health: 4 Flammability: 2 Reactivity: 0
Label Hazard Warning:
POISON! DANGER! MAY BE FATAL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN.
RAPIDLY ABSORBED THROUGH SKIN. CORROSIVE. CAUSES SEVERE BURNS TO EVERY AREA
OF CONTACT. AFFECTS CENTRAL NERVOUS SYSTEM, LIVER AND KIDNEYS. COMBUSTIBLE.
Label Precautions:
Do not breathe dust.
Do not get in eyes, on skin, or on clothing.
Keep container closed.
Use only with adequate ventilation.
Wash thoroughly after handling.
Keep away from heat, sparks and flame.
Label First Aid:
IN ALL CASES, GET MEDICAL ATTENTION IMMEDIATELY. KEEP A PHENOL ANTIDOTE KIT
in area of product use or storage. Administer castor oil and/or polyethylene
glycol per pre-planned directions. If swallowed, immediately administer
castor oil or other vegetable oil. Never give anything by mouth to an
unconscious person. In case of skin contact, immediately flush skin with
large amounts of water while removing contaminated clothing and shoes. As
soon as possible, repeatedly apply polyethylene glycol to affected area.
Destroy contaminated clothing and shoes. If inhaled, remove to fresh air. If
not breathing, give artificial respiration. If breathing is difficult, give
oxygen. In case of eye contact, immediately flush eyes with plenty of water
for at least 15 minutes while lifting lower and upper eyelids.
Product Use:
Laboratory Reagent.
Revision Information:
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in
good faith but makes no representation as to its comprehensiveness or accuracy.
This document is intended only as a guide to the appropriate precautionary
handling of the material by a properly trained person using this product.
Individuals receiving the information must exercise their independent judgment
in determining its appropriateness for a particular purpose. MALLINCKRODT
BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED,
INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A
PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE
PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC.
WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS
INFORMATION.
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Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)