POTASSIUM PHOSPHATE TRIBASIC, N-HYDRATE

MSDS Number: P6060 --- Effective Date: 12/08/96


1. Product Identification

Synonyms: Phosphoric acid tripotassium salt; tripotassium phosphate
CAS No.: 7778-53-2
Molecular Weight: 212.27 (Anhydrous)
Chemical Formula: K3PO4 . nH2O
Product Codes: 3256


2. Composition/Information on Ingredients


  Ingredient                                CAS No         Percent   Hazardous                                       
  ---------------------------------------   ------------   -------   ---------        
 
  Potassium Phosphate Tribasic              7778-53-2      90 - 100%    Yes                                                                  
 


3. Hazards Identification

Emergency Overview
--------------------------
WARNING! HARMFUL IF SWALLOWED OR INHALED. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT.


J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 2 - Moderate
Flammability Rating: 0 - None
Reactivity Rating: 1 - Slight
Contact Rating: 2 - Moderate
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES
Storage Color Code: Orange (General Storage)
-----------------------------------------------------------------------------------------------------------

Potential Health Effects
----------------------------------

Inhalation:
Causes irritation to the respiratory tract. Symptoms may include coughing, shortness of breath.

Ingestion:
Phosphates are slowly and incompletely absorbed when ingested, and seldom result in systemic effects. Such effects, however, have occurred. Symptoms may include vomiting, lethargy, diarrhea, blood chemistry effects, cardiac effects and central nervous system effects. The toxicity of phosphates is because of their ability to sequester calcium. Acute potassium intoxication by mouth is rare because large single doses usually induce vomiting and because in the absence of pre-existing kidney damage, potassium is rapidly excreted. Potassium poisoning can result in heart effects, change in respiration rate, tingling in the extremities, heaviness in the limbs, nausea and diarrhea.

Skin Contact:
Causes irritation to skin. Symptoms include redness, itching, and pain.

Eye Contact:
Causes irritation, redness, and pain.

Chronic Exposure:
May sequester calcium and cause calcium phosphate deposits in the kidneys. Continued ingestion or absorption of phosphate and potassium can lead to renal disorders and in acute cases, potassium poisoning. The latter can involve circulatory complications, partial paralysis and ulcers of the stomach.

Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders or eye problems, or impaired liver, kidney or respiratory function may be more susceptible to the effects of the substance.


4. First Aid Measures

Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.

Ingestion:
Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention.

Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.

Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.


5. Fire Fighting Measures

Fire:
Not considered to be a fire hazard.

Explosion:
Not considered to be an explosion hazard.

Fire Extinguishing Media:
Use any means suitable for extinguishing surrounding fire.

Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.


6. Accidental Release Measures

Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Spills: Sweep up and containerize for reclamation or disposal. Vacuuming or wet sweeping may be used to avoid dust dispersal.


7. Handling and Storage

Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product.


8. Exposure Controls/Personal Protection

Airborne Exposure Limits:
- OSHA Permissible Exposure Limit (PEL): 15 mg/m3 total dust, 5 mg/m3 respirable fraction for nuisance dusts. - ACGIH Threshold Limit Value (TLV): 10 mg/m3 total dust containing no asbestos and < 1% crystalline silica for Particulates Not Otherwise Classified (PNOC).

Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.

Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded, a full facepiece respirator with dust/mist filter may be worn up to 50 times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres.

Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.

Eye Protection:
Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.


9. Physical and Chemical Properties

Appearance:
White powder.

Odor:
Odorless.

Solubility:
50 grams in 100 grams of water.

Specific Gravity:
2.564 @ 17C/4C

pH:
Strongly alkaline.

% Volatiles by volume @ 21C (70F):
0

Boiling Point:
Not applicable.

Melting Point:
ca. 1340C (ca. 2444F)

Vapor Density (Air=1):
No information found.

Vapor Pressure (mm Hg):
No information found.

Evaporation Rate (BuAc=1):
No information found.


10. Stability and Reactivity

Stability:
Stable under ordinary conditions of use and storage.

Hazardous Decomposition Products:
Phosphorus oxides may form when heated to decomposition.

Hazardous Polymerization:
Will not occur.

Incompatibilities:
Acidic materials.

Conditions to Avoid:
Incompatibles.


11. Toxicological Information


No LD50/LC50 information found relating to normal routes of occupational exposure.

  --------\Cancer Lists\------------------------------------------------------
                                         ---NTP Carcinogen---
  Ingredient                             Known    Anticipated    IARC Category
  ------------------------------------   -----    -----------    -------------
  Potassium Phosphate Tribasic            No          No            None
  (7778-53-2)                         


12. Ecological Information

Environmental Fate:
No information found.

Environmental Toxicity:
No information found.


13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.


14. Transport Information

Not regulated.


15. Regulatory Information


  --------\Chemical Inventory Status - Part 1\---------------------------------
  Ingredient                                       TSCA  EC   Japan  Australia
  -----------------------------------------------  ----  ---  -----  ---------
  Potassium Phosphate Tribasic (7778-53-2)          Yes  Yes   Yes      Yes                                      
 
  --------\Chemical Inventory Status - Part 2\---------------------------------
                                                          --Canada--
  Ingredient                                       Korea  DSL   NDSL  Phil.
  -----------------------------------------------  -----  ---   ----  -----
  Potassium Phosphate Tribasic (7778-53-2)          Yes   Yes   No     Yes                             
 
  --------\Federal, State & International Regulations - Part 1\----------------
                                             -SARA 302-    ------SARA 313------
  Ingredient                                 RQ    TPQ     List  Chemical Catg.
  -----------------------------------------  ---   -----   ----  --------------
  Potassium Phosphate Tribasic (7778-53-2)   No    No      No         No
 
  --------\Federal, State & International Regulations - Part 2\----------------
                                                        -RCRA-    -TSCA-
  Ingredient                                 CERCLA     261.33     8(d) 
  -----------------------------------------  ------     ------    ------
  Potassium Phosphate Tribasic               No         No         No        
  (7778-53-2)                             
 
 
Chemical Weapons Convention:  No     TSCA 12(b):  No     CDTA:  No
SARA 311/312:  Acute: Yes      Chronic: No   Fire: No  Pressure: No
Reactivity: No          (Pure / Solid) 


Australian Hazchem Code: No information found.
Poison Schedule: S5

WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.


16. Other Information

NFPA Ratings: Health: 2 Flammability: 0 Reactivity: 0

Label Hazard Warning:
WARNING! HARMFUL IF SWALLOWED OR INHALED. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT.

Label Precautions:
Avoid contact with eyes, skin and clothing. Avoid breathing dust. Keep container closed. Use only with adequate ventilation. Wash thoroughly after handling.

Label First Aid:
In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. If swallowed, induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. In all cases, get medical attention.

Product Use:
Laboratory Reagent.

Revision Information:
Pure. New 16 section MSDS format, all sections have been revised.

Disclaimer:
************************************************************************************************ Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
************************************************************************************************ Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)