N-PROPYL ALCOHOL

MSDS Number: P6390 --- Effective Date: 12/08/96


1. Product Identification

Synonyms: 1-Propanol; Ethyl Carbinol; 1-Hydroxypropane; n-Propanol
CAS No.: 71-23-8
Molecular Weight: 60.1
Chemical Formula: CH3(CH2)2 OH
Product Codes: J.T. Baker: 9031, 9086, 9087 Mallinckrodt: 5351, 5919, 7169


2. Composition/Information on Ingredients


  Ingredient                                CAS No         Percent   Hazardous                                       
  ---------------------------------------   ------------   -------   ---------        
 
  Propyl Alcohol                            71-23-8          100%       Yes                                                               
 


3. Hazards Identification

Emergency Overview
--------------------------
WARNING! FLAMMABLE LIQUID AND VAPOR. HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. MAY AFFECT CENTRAL NERVOUS SYSTEM. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT.


J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 1 - Slight
Flammability Rating: 3 - Severe (Flammable)
Reactivity Rating: 1 - Slight
Contact Rating: 2 - Moderate
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES; CLASS B EXTINGUISHER
Storage Color Code: Red (Flammable)
-----------------------------------------------------------------------------------------------------------

Potential Health Effects
----------------------------------

Inhalation:
Vapors have a mild narcotic effect and act as an upper respiratory tract irritant. Symptoms may include irritation of the eyes, nose, and throat, drowsiness, headache, and incoordination. Excessive exposures may lead to narcosis and central nervous system depression.

Ingestion:
May cause nausea, vomiting, drowsiness, gastrointestinal pain, cramps and diarrhea. Large doses may cause death.

Skin Contact:
Defatting agent. May cause skin irritation. Skin absorption may occur with symptoms paralleling those from inhalation exposure.

Eye Contact:
Vapors are irritating to the eyes. Splashes may cause severe irritation, with stinging, tearing, redness and pain.

Chronic Exposure:
Prolonged or repeated skin contact may cause dermatitis. No systemic chronic effects have been reported in humans.

Aggravation of Pre-existing Conditions:
Persons with pre-existing skin problems or impaired respiratory function may be more susceptible to the effects of this substance.


4. First Aid Measures

Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.

Ingestion:
Give large amounts of water to drink. Never give anything by mouth to an unconscious person. Get medical attention.

Skin Contact:
In case of contact, immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. Call a physician.

Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.

Note to Physician:
Treat CNS depression supportively. Rule out other causes. Treat ingestion with gastric lavage and saline catharsis. Metabolite acetone may be detected in urine.


5. Fire Fighting Measures

Fire:
Flash point: 23C (73F) CC Autoignition temperature: 412C (774F) Flammable limits in air % by volume: lel: 2.3; uel: 13.7 Flammable Liquid and Vapor!

Explosion:
Above flash point, vapor-air mixtures are explosive within flammable limits noted above. Vapors can flow along surfaces to distant ignition source and flash back. Ignites on contact with potassium tertbutoxide.

Fire Extinguishing Media:
Water spray, dry chemical, alcohol foam, or carbon dioxide. Water spray may be used to keep fire exposed containers cool.

Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. If a leak or spill has not ignited, use water spray to disperse the vapors, to protect personnel attempting to stop leak, and to flush spills away from exposures.


6. Accidental Release Measures

Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel from entering. Contain and recover liquid when possible. Use non-sparking tools and equipment. Collect liquid in an appropriate container or absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a chemical waste container. Do not use combustible materials, such as saw dust. Do not flush to sewer! Water can be used to dilute to raise flashpoint and to flush away from possible sources of ignition. J. T. Baker SOLUSORB(tm) solvent adsorbent is recommended for spills of this product.


7. Handling and Storage

Protect against physical damage. Store in a cool, dry well-ventilated location, away from any area where the fire hazard may be acute. Outside or detached storage is preferred. Separate from incompatibles. Containers should be bonded and grounded for transfers to avoid static sparks. Storage and use areas should be No Smoking areas. Use non-sparking type tools and equipment, including explosion proof ventilation. Containers of this material may be hazardous when empty since they retain product residues (vapors, liquid); observe all warnings and precautions listed for the product.


8. Exposure Controls/Personal Protection

Airborne Exposure Limits:
-OSHA Permissible Exposure Limit (PEL): 200 ppm (TWA), 250 ppm (STEL) -ACGIH Threshold Limit Value (TLV): 200 ppm (TWA), 250 ppm (STEL) skin

Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.

Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded, a full facepiece respirator with organic vapor cartridge may be worn up to 50 times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres. This compound possibly exists in both particulate and vapor phase. A dust/mist prefilter should be used for the particulate.

Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.

Eye Protection:
Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.


9. Physical and Chemical Properties

Appearance:
Clear, colorless liquid.

Odor:
Alcohol odor.

Solubility:
Infinitely soluble.

Specific Gravity:
0.804

pH:
No information found.

% Volatiles by volume @ 21C (70F):
100

Boiling Point:
97C (207F)

Melting Point:
-127C (-197F)

Vapor Density (Air=1):
2.07

Vapor Pressure (mm Hg):
21 @ 25C (77F)

Evaporation Rate (BuAc=1):
1.3


10. Stability and Reactivity

Stability:
Stable under ordinary conditions of use and storage.

Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition. May produce acrid smoke and irritating fumes when heated to decomposition.

Hazardous Polymerization:
Will not occur.

Incompatibilities:
Reacts violently with potassium-tert-butoxide. Can react vigorously with oxidizing materials.

Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.


11. Toxicological Information


Oral Rat LD50: 1870 mg/kg; Skin Rabbit LD50: 4060 mg/kg; Inhalation mouse LC50: 48 mg/m3; Irritation,open, eye rabbit 4mg, Severe; open, skin, rabbit: 580 mg/24 Hr. Mild; Investigated as a tumorigen, a mutagen, and a reproductive effector.

  --------\Cancer Lists\------------------------------------------------------
                                         ---NTP Carcinogen---
  Ingredient                             Known    Anticipated    IARC Category
  ------------------------------------   -----    -----------    -------------
  Propyl Alcohol (71-23-8)                No          No            None


12. Ecological Information

Environmental Fate:
When released into the soil, this material is expected to readily biodegrade. When released into the soil, this material is expected to leach into groundwater. When released into the soil, this material is expected to quickly evaporate. When released into water, this material is expected to readily biodegrade. When released to water, this material is expected to quickly evaporate. This material is not expected to significantly bioaccumulate. This material has a log octanol-water partition coefficient of less than 3.0. When released into the water, this material is expected to have a half-life between 1 and 10 days. When released into the air, this material is expected to be readily degraded by reaction with photochemically produced hydroxyl radicals. When released into the air, this material is expected to be readily removed from the atmosphere by wet deposition.

Environmental Toxicity:
The LC50/96-hour values for fish are between 1 and 10 mg/l. This material is expected to be toxic to aquatic life.


13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and sent to a RCRA approved incinerator or disposed in a RCRA approved waste facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.


14. Transport Information

Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: PROPANOL
Hazard Class: 3
UN/NA: UN1274
Packing Group: II
Information reported for product/size: 370LB

International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: PROPANOL
Hazard Class: 3.2
UN/NA: UN1274
Packing Group: II
Information reported for product/size: 370LB



15. Regulatory Information


  --------\Chemical Inventory Status - Part 1\---------------------------------
  Ingredient                                       TSCA  EC   Japan  Australia
  -----------------------------------------------  ----  ---  -----  ---------
  Propyl Alcohol (71-23-8)                          Yes  Yes   Yes      Yes                                      
 
  --------\Chemical Inventory Status - Part 2\---------------------------------
                                                          --Canada--
  Ingredient                                       Korea  DSL   NDSL  Phil.
  -----------------------------------------------  -----  ---   ----  -----
  Propyl Alcohol (71-23-8)                          Yes   Yes   No     Yes                             
 
  --------\Federal, State & International Regulations - Part 1\----------------
                                             -SARA 302-    ------SARA 313------
  Ingredient                                 RQ    TPQ     List  Chemical Catg.
  -----------------------------------------  ---   -----   ----  --------------
  Propyl Alcohol (71-23-8)                   No    No      No         No
 
  --------\Federal, State & International Regulations - Part 2\----------------
                                                        -RCRA-    -TSCA-
  Ingredient                                 CERCLA     261.33     8(d) 
  -----------------------------------------  ------     ------    ------
  Propyl Alcohol (71-23-8)                   No         No         No                   
 
 
Chemical Weapons Convention:  No     TSCA 12(b):  No     CDTA:  No
SARA 311/312:  Acute: Yes      Chronic: Yes  Fire: Yes Pressure: No
Reactivity: No          (Pure / Liquid)


Australian Hazchem Code: 2[S]E
Poison Schedule: No information found.

WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.


16. Other Information

NFPA Ratings: Health: 1 Flammability: 3 Reactivity: 0

Label Hazard Warning:
WARNING! FLAMMABLE LIQUID AND VAPOR. HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. MAY AFFECT CENTRAL NERVOUS SYSTEM. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT.

Label Precautions:
Keep away from heat, sparks and flame. Avoid breathing vapor. Avoid contact with eyes, skin and clothing. Keep container closed. Use with adequate ventilation. Wash thoroughly after handling.

Label First Aid:
In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. If swallowed, give large amounts of water to drink. Never give anything by mouth to an unconscious person. In all cases call a physician.

Product Use:
Laboratory Reagent.

Revision Information:
Pure. New 16 section MSDS format, all sections have been revised.

Disclaimer:
************************************************************************************************ Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
************************************************************************************************ Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)