SAPONIN
MSDS Number: S0746 --- Effective Date: 12/08/96
1. Product Identification
Synonyms: Saponins from 'Quillaja Molina' ; Quillaja extract;
Quillaja Saponin
CAS No.: 74499-23-3
Molecular Weight: Not applicable to mixtures.
Chemical Formula: Not applicable.
Product Codes: J.T. Baker:
3388
Mallinckrodt:
H277
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Saponin 74499-23-3 100% Yes
3. Hazards Identification
Emergency Overview
--------------------------
WARNING! HARMFUL IF SWALLOWED OR INHALED. CAUSES IRRITATION TO SKIN,
EYES AND RESPIRATORY TRACT.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 1 - Slight
Flammability Rating: 1 - Slight
Reactivity Rating: 0 - None
Contact Rating: 1 - Slight
Lab Protective Equip: GOGGLES; LAB COAT
Storage Color Code: Orange (General Storage)
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Potential Health Effects
----------------------------------
Information on the human health effects from exposure to this substance is
limited.
Inhalation:
When dispersed in air, Quillaja saponin causes sneezing and may irritate
the respiratory tract.
Ingestion:
Moderately toxic by ingestion. Acts as a powerful hemolytic when injected
into the blood stream, dissolving red corpuscles even at extreme dilutions.
Skin Contact:
Causes irritation to skin. Symptoms include redness, itching, and pain.
Eye Contact:
Causes irritation, redness, and pain.
Chronic Exposure:
No information found.
Aggravation of Pre-existing Conditions:
No information found.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical attention.
Ingestion:
Induce vomiting immediately as directed by medical personnel. Never give
anything by mouth to an unconscious person. Get medical attention.
Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes. Remove
contaminated clothing and shoes. Get medical attention. Wash clothing
before reuse. Thoroughly clean shoes before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes,
lifting lower and upper eyelids occasionally. Get medical attention
immediately.
5. Fire Fighting Measures
Fire:
As with most organic solids, fire is possible at elevated temperatures or
by contact with an ignition source.
Explosion:
Fine dust dispersed in air in sufficient concentrations, and in the
presence of an ignition source is a potential dust explosion hazard.
Fire Extinguishing Media:
Water spray, dry chemical, alcohol foam, or carbon dioxide.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved
self-contained breathing apparatus with full facepiece operated in the
pressure demand or other positive pressure mode.
6. Accidental Release Measures
Remove all sources of ignition. Ventilate area of leak or spill. Wear
appropriate personal protective equipment as specified in Section 8.
Spills: Clean up spills in a manner that does not disperse dust into the
air. Use non-sparking tools and equipment. Reduce airborne dust and prevent
scattering by moistening with water. Pick up spill for recovery or disposal
and place in a closed container.
7. Handling and Storage
Keep in a tightly closed container, stored in a cool, dry, ventilated area.
Protect against physical damage. Containers of this material may be
hazardous when empty since they retain product residues (dust, solids);
observe all warnings and precautions listed for the product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
None established.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee
exposures as low as possible. Local exhaust ventilation is generally
preferred because it can control the emissions of the contaminant at its
source, preventing dispersion of it into the general work area. Please
refer to the ACGIH document, Industrial Ventilation, A Manual of
Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
For conditions of use where exposure to the dust or mist is apparent, a
half-face dust/mist respirator may be worn. For emergencies or instances
where the exposure levels are not known, use a full-face positive-pressure,
air-supplied respirator. WARNING: Air-purifying respirators do not
protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat,
apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or full face shield where dusting or
splashing of solutions is possible. Maintain eye wash fountain and
quick-drench facilities in work area.
9. Physical and Chemical Properties
Appearance:
Yellow to yellow-tan crystalline powder.
Odor:
Characteristic irritating odor.
Solubility:
Soluble in water.
Specific Gravity:
No information found.
pH:
No information found.
% Volatiles by volume @ 21C (70F):
0
Boiling Point:
No information found.
Melting Point:
No information found.
Vapor Density (Air=1):
No information found.
Vapor Pressure (mm Hg):
No information found.
Evaporation Rate (BuAc=1):
No information found.
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizers.
Conditions to Avoid:
Incompatibles.
11. Toxicological Information
No LD50/LC50 information found relating to normal routes of occupational
exposure. Investigated as a reproductive effector.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Saponin (74499-23-3) No No None
12. Ecological Information
Environmental Fate:
No information found.
Environmental Toxicity:
No information found.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an
appropriate and approved waste disposal facility. Processing, use or
contamination of this product may change the waste management options.
State and local disposal regulations may differ from federal disposal
regulations.
Dispose of container and unused contents in accordance with federal, state
and local requirements.
14. Transport Information
Not regulated.
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Saponin (74499-23-3) Yes No No Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Saponin (74499-23-3) No Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Saponin (74499-23-3) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Saponin (74499-23-3) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: No Fire: No Pressure: No
Reactivity: No (Mixture / Solid)
Australian Hazchem Code: No information found.
Poison Schedule: No information found.
WHMIS:
This MSDS has been prepared according to the hazard criteria of
the Controlled Products Regulations (CPR) and the MSDS contains
all of the information required by the CPR.
16. Other Information
NFPA Ratings:
Health: 1 Flammability: 1 Reactivity: 0
Label Hazard Warning:
WARNING! HARMFUL IF SWALLOWED OR INHALED. CAUSES IRRITATION TO SKIN, EYES AND
RESPIRATORY TRACT.
Label Precautions:
Avoid breathing dust.
Avoid contact with eyes, skin and clothing.
Keep container closed.
Use only with adequate ventilation.
Wash thoroughly after handling.
Label First Aid:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. In case of contact,
immediately flush eyes or skin with plenty of water for at least 15 minutes.
Remove contaminated clothing and shoes. Wash clothing before reuse. If
swallowed, induce vomiting immediately as directed by medical personnel.
Never give anything by mouth to an unconscious person. In all cases, get
medical attention.
Product Use:
Laboratory Reagent.
Revision Information:
Mixture. New 16 section MSDS format, all sections have been revised.
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in good
faith but makes no representation as to its comprehensiveness or accuracy. This
document is intended only as a guide to the appropriate precautionary handling
of the material by a properly trained person using this product. Individuals
receiving the information must exercise their independent judgment in
determining its appropriateness for a particular purpose. MALLINCKRODT BAKER,
INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED,
INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A
PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE
PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC.
WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS
INFORMATION.
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Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)