SODIUM FLUORIDE

MSDS Number: S3722 --- Effective Date: 02/16/98


1. Product Identification

Synonyms: Floridine; sodium monofluoride; disodium difluoride; natrium fluoride; Florocid
CAS No.: 7681-49-4
Molecular Weight: 41.99
Chemical Formula: NaF
Product Codes:
J.T. Baker: 3687, 3688, 3689
Mallinckrodt: 0467, 5325, 7636

2. Composition/Information on Ingredients


  Ingredient                                CAS No         Percent   Hazardous                                       
  ---------------------------------------   ------------   -------   ---------        
 
  Sodium Fluoride                           7681-49-4        100%       Yes                                                               
 

3. Hazards Identification

Emergency Overview
--------------------------
DANGER! MAY BE FATAL IF SWALLOWED OR INHALED. AFFECTS RESPIRATORY SYSTEM, HEART, SKELETON, CIRCULATORY SYSTEM, CENTRAL NERVOUS SYSTEM AND KIDNEYS. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT. IRRITATION EFFECTS MAY BE DELAYED.

J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 3 - Severe (Poison)
Flammability Rating: 0 - None
Reactivity Rating: 1 - Slight
Contact Rating: 2 - Moderate
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES
Storage Color Code: Blue (Health)
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Potential Health Effects
----------------------------------

If inhaled or swallowed, this compound can cause fluoride poisoning. Early symptoms include nausea, vomiting, diarrhea, and weakness. Later effects include central nervous system effects, cardiovascular effects and death.

Inhalation:
Causes severe irritation to the respiratory tract, symptoms may include coughing, sore throat, and labored breathing. May be absorbed through inhalation of dust; symptoms may parallel those from ingestion exposure. Irritation effects may not appear immediately.
Ingestion:
Toxic! May cause salivation, nausea, vomiting, diarrhea, and abdominal pain. Symptoms of weakness, tremors, shallow respiration, cardopedal spasm, convulsions, and coma may follow. May cause brain and kidney damage. Affects heart and circulatory system. Death may occur from respiratory paralysis. Estimated lethal dose = 5-l0 grams.
Skin Contact:
Causes irritation, with redness and pain. Solutions are corrosive. Effects may not appear immediately.
Eye Contact:
Eye irritant! May cause irritation and serious eye damage. Effects may not immediately appear.
Chronic Exposure:
Chronic exposure may cause mottling of teeth and bone damage (osteosclerosis) and fluorosis. Symptoms of fluorisis include brittle bones,weight loss, anemia, calcified ligaments, general ill health and joint stiffness.
Aggravation of Pre-existing Conditions:
Populations that appear to be at increased risk from the effects of fluoride are individuals that suffer from diabetes insipidus or some forms of renal impairment.

4. First Aid Measures

First aid procedures should be pre-planned for fluoride compound emergencies.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. CALL A PHYSICIAN IMMEDIATELY.
Ingestion:
Administer milk, chewable calcium carbonate tablets or milk of magnesia. Never give anything by mouth to an unconscious person. CALL A PHYSICIAN IMMEDIATELY.
Skin Contact:
Wipe off any excess material from skin and then immediately flush skin with large amounts of soapy water. Remove contaminated clothing and shoes. Wash clothing before re-use. Apply bandages soaked in magnesium sulfate. CALL A PHYSICIAN IMMEDIATELY.
Eye Contact:
Immediately flush eyes with gentle but large stream of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Call a physician immediately.

Note to Physician:
For large exposures, systemic effects (hypocalcemia and hypomagnesia) may occur.

5. Fire Fighting Measures

Fire:
Not considered to be a fire hazard.
Explosion:
Not considered to be an explosion hazard.
Fire Extinguishing Media:
Use any means suitable for extinguishing surrounding fire.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.

6. Accidental Release Measures

Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Spills: Pick up and place in a suitable container for reclamation or disposal, using a method that does not generate dust. US Regulations (CERCLA) require reporting spills and releases to soil, water and air in excess of reportable quantities. The toll free number for the US Coast Guard National Response Center is (800) 424-8802.


7. Handling and Storage

Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Separate from acids and oxidizing materials. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product.

8. Exposure Controls/Personal Protection

Airborne Exposure Limits:
-OSHA Permissible Exposure Limit (PEL):
2.5 mg(F)/m3 (TWA)

-ACGIH Threshold Limit Value (TLV):
2.5 mg(F)/m3 (TWA)
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded, a half-face dust/mist respirator may be worn for up to ten times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. A full-face piece dust/mist respirator may be worn up to 50 times the exposure limit, or the maximum use concentration specified by the appropriate regulatory agency, or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.

9. Physical and Chemical Properties

Appearance:
White crystals.
Odor:
Odorless.
Solubility:
4 g/100 ml water @ 15C (59F)
Specific Gravity:
2.78
pH:
No information found.
% Volatiles by volume @ 21C (70F):
0
Boiling Point:
1700C (3092F)
Melting Point:
993C (1819F)
Vapor Density (Air=1):
No information found.
Vapor Pressure (mm Hg):
1 @ 1077C (1971F)
Evaporation Rate (BuAc=1):
No information found.

10. Stability and Reactivity

Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Burning may produce hydrogen fluoride vapors.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Reacts with acids to form hydrogen fluoride.
Conditions to Avoid:
No information found.

11. Toxicological Information


Oral rat LD50: 52 mg/kg; Eye Rabbit (standard Draize) 20mg/24-hr, moderate; Investigated as a tumorigen, mutagen, reproductive effector
  --------\Cancer Lists\------------------------------------------------------
                                         ---NTP Carcinogen---
  Ingredient                             Known    Anticipated    IARC Category
  ------------------------------------   -----    -----------    -------------
  Sodium Fluoride (7681-49-4)             No          No            None

12. Ecological Information

Environmental Fate:
No information found.
Environmental Toxicity:
This material is not expected to be toxic to aquatic life. The LC50/96-hour values for fish are over 100 mg/l. LD50, oral (goat, sheep) 100 mg/kg; LD50, oral (wild bird) 110 mg/kg.

13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.

14. Transport Information

Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: SODIUM FLUORIDE
Hazard Class: 6.1
UN/NA: UN1690
Packing Group: III
Information reported for product/size: 250LB

International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: SODIUM FLUORIDE, SOLID
Hazard Class: 6.1
UN/NA: UN1690
Packing Group: III
Information reported for product/size: 250LB


15. Regulatory Information

  --------\Chemical Inventory Status - Part 1\---------------------------------
  Ingredient                                       TSCA  EC   Japan  Australia
  -----------------------------------------------  ----  ---  -----  ---------
  Sodium Fluoride (7681-49-4)                       Yes  Yes   Yes      Yes                                      
 
  --------\Chemical Inventory Status - Part 2\---------------------------------
                                                          --Canada--
  Ingredient                                       Korea  DSL   NDSL  Phil.
  -----------------------------------------------  -----  ---   ----  -----
  Sodium Fluoride (7681-49-4)                       Yes   Yes   No     Yes                             
 
  --------\Federal, State & International Regulations - Part 1\----------------
                                             -SARA 302-    ------SARA 313------
  Ingredient                                 RQ    TPQ     List  Chemical Catg.
  -----------------------------------------  ---   -----   ----  --------------
  Sodium Fluoride (7681-49-4)                No    No      No         No
 
  --------\Federal, State & International Regulations - Part 2\----------------
                                                        -RCRA-    -TSCA-
  Ingredient                                 CERCLA     261.33     8(d) 
  -----------------------------------------  ------     ------    ------
  Sodium Fluoride (7681-49-4)                1000       No         No                   
 
 
Chemical Weapons Convention:  Yes    TSCA 12(b):  No     CDTA:  No
SARA 311/312:  Acute: Yes      Chronic: Yes  Fire: No  Pressure: No
Reactivity: No          (Pure / Solid) 


Australian Hazchem Code: 2Z
Poison Schedule: S2
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.

16. Other Information

NFPA Ratings: Health: 3 Flammability: 0 Reactivity: 0
Label Hazard Warning:
DANGER! MAY BE FATAL IF SWALLOWED OR INHALED. AFFECTS RESPIRATORY SYSTEM, HEART, SKELETON, CIRCULATORY SYSTEM, CENTRAL NERVOUS SYSTEM AND KIDNEYS. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT. IRRITATION EFFECTS MAY BE DELAYED.
Label Precautions:
Do not breathe dust.
Keep container closed.
Use only with adequate ventilation.
Wash thoroughly after handling.
Avoid contact with eyes, skin and clothing.
Label First Aid:
In all cases call a physician immediately. First Aid procedures should be pre-planned for fluoride compound emergencies. If swallowed, administer milk, chewable calcium carbonate tablets or milk of magnesia. Never give anything by mouth to an unconscious person. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing difficult, give artificial respiration. In case of skin contact wipe off any excess material then immediately flush skin with large amounts of soapy water. Remove contaminated clothing and shoes. Wash clothing before re-use. Apply bandages soaked in magnesium sulfate. In case of eye contact, immediately flush eyes with gentle but large stream of water for at least 15 minutes, lifting upper and lower eyelids occasionally.
Product Use:
Laboratory Reagent.
Revision Information:
MSDS Section(s) changed since last revision of document include: 14, 15.
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
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Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)