International Chemical Safety Cards

PROPYLENE OXIDE ICSC: 0192
PROPYLENE OXIDE
1,2-Epoxypropane
Methyloxirane
Methyl ethylene oxide
Propene oxide
CH3CHCH2O/C3H6O
Molecular mass: 58.1
CAS # 75-56-9
RTECS # TZ2975000
ICSC # 0192
UN # 1280
EC # 603-055-00-4

TYPES OF
HAZARD/
EXPOSURE
ACUTE HAZARDS/
SYMPTOMS
PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Extremely flammable. Heating will cause rise in pressure with risk of bursting.
NO open flames, NO sparks, and NO smoking.
Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION Vapour/air mixtures are explosive.
Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling. Use non-sparking handtools.
In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position.
EXPOSURE
STRICT HYGIENE!

  • INHALATION
  • Cough. Sore throat.
    Ventilation, local exhaust, or breathing protection.
    Fresh air, rest.
  • SKIN
  • Redness.
    Protective gloves. Protective clothing.
    Remove contaminated clothes. Rinse skin with plenty of water or shower.
  • EYES
  • Redness. Pain.
    Safety goggles or eye protection in combination with breathing protection.
    First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
  • INGESTION

  • Do not eat, drink, or smoke during work. Wash hands before eating.
    Rinse mouth. Give plenty of water to drink. Refer for medical attention.
    SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
    Evacuate danger area! Consult an expert! Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer (extra personal protection: complete protective clothing including self-contained breathing apparatus).
    Fireproof. Separated from acids, bases, oxidants. Cool.
    Unbreakable packaging; put breakable packaging into closed unbreakable container.
    F+ symbol
    T symbol
    R: 45-12-20/21/22-36/37/38
    S: 53-45
    Note: E
    UN Hazard Class: 3
    UN Packing Group: I
    SEE IMPORTANT INFORMATION ON BACK
    ICSC: 0192 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993

    International Chemical Safety Cards

    PROPYLENE OXIDE ICSC: 0192

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    PHYSICAL STATE; APPEARANCE:
    VERY VOLATILE COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR.

    PHYSICAL DANGERS:
    The vapour is heavier than air and may travel along the ground; distant ignition possible.

    CHEMICAL DANGERS:
    The substance may polymerize violently under the influence of bases, acids and metal chlorides with fire or explosion hazard. Reacts violently with chlorine, ammonia, strong oxidants, acids causing fire and explosion hazard.

    OCCUPATIONAL EXPOSURE LIMITS (OELs):
    TLV: 20 ppm; 48 mg/m3 (as TWA) (ACGIH 1994-1995).


    ROUTES OF EXPOSURE:
    The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

    INHALATION RISK:
    A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20C.

    EFFECTS OF SHORT-TERM EXPOSURE:
    The substance irritates the eyes, the skin and the respiratory tract.

    EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
    Repeated or prolonged contact may cause skin sensitization. This substance is possibly carcinogenic to humans.
    PHYSICAL
    PROPERTIES
    Boiling point: 34C
    Melting point: -104C
    Relative density (water = 1): 0.8
    Solubility in water, g/100 ml at 20C: 40.5
    Vapour pressure, kPa at 20C: 59
    Relative vapour density (air = 1): 2.0
    Relative density of the vapour/air-mixture at 20C (air = 1): 1.6
    Flash point: -37C c.c.
    Auto-ignition temperature: 449C
    Explosive limits, vol% in air: 2-38.5
    Octanol/water partition coefficient as log Pow: 0.03
    ENVIRONMENTAL
    DATA

    N O T E S
    No odour warning if toxic concentrations are present.
    Transport Emergency Card: TEC (R)-158
    NFPA Code: H2; F4; R2
    ADDITIONAL INFORMATION


    ICSC: 0192 PROPYLENE OXIDE
    © IPCS, CEC, 1993
    IMPORTANT LEGAL NOTICE: Neither the CEC or the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use.