International Chemical Safety Cards

N-METHYL-2-PYRROLIDONE ICSC: 0513
N-METHYL-2-PYRROLIDONE
1-Methyl-2-pyrrolidinone
1-Methyl-2-pyrrolidone
N-Methylpyrrolidone
C5H9NO
Molecular mass: 99.1
CAS # 872-50-4
RTECS # UY5790000
ICSC # 0513
EC # 606-021-00-7

TYPES OF
HAZARD/
EXPOSURE
ACUTE HAZARDS/
SYMPTOMS
PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION Above 96C explosive vapour/air mixtures may be formed.
Above 96C use a closed system, ventilation.

EXPOSURE
PREVENT GENERATION OF MISTS!

  • INHALATION
  • Headache.
    Ventilation.
    Fresh air, rest. Refer for medical attention.
  • SKIN
  • MAY BE ABSORBED! Dry skin. Redness.
    Protective gloves. Protective clothing.
    Remove contaminated clothes. Rinse skin with plenty of water or shower.
  • EYES
  • Redness. Pain. Blurred vision.
    Safety spectacles.
    First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
  • INGESTION

  • Do not eat, drink, or smoke during work.
    Rinse mouth. Do NOT induce vomiting. Refer for medical attention.
    SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
    Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place (extra personal protection: filter respirator for organic gases and vapours).
    Separated from oxidants, rubber, plastics, aluminium, light metals. Dry. Ventilation along the floor.

    Xi symbol
    R: 36/38
    S: (2)-41
    SEE IMPORTANT INFORMATION ON BACK
    ICSC: 0513 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993

    International Chemical Safety Cards

    N-METHYL-2-PYRROLIDONE ICSC: 0513

    I

    M

    P

    O

    R

    T

    A

    N

    T



    D

    A

    T

    A

    PHYSICAL STATE; APPEARANCE:
    COLOURLESS HYGROSCOPIC LIQUID , WITH CHARACTERISTIC ODOUR. TURNS YELLOW ON EXPOSURE TO HEAT.

    PHYSICAL DANGERS:


    CHEMICAL DANGERS:
    The substance decomposes on heating or on burning producing toxic fumes including nitrogen oxides, carbon monoxide. Attacks aluminium, light metals, rubber, plastic.

    OCCUPATIONAL EXPOSURE LIMITS (OELs):
    TLV not established.
    MAK: 20 ppm; 80 mg/m3; skin (1996).


    ROUTES OF EXPOSURE:
    The substance can be absorbed into the body by inhalation and through the skin.

    INHALATION RISK:
    A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20C, on spraying however much quickly.

    EFFECTS OF SHORT-TERM EXPOSURE:
    The substance irritates the eyes and the skin. Swallowing the liquid may cause aspiration into the lungs with the risk of chemical pneumonitis.

    EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
    Repeated or prolonged contact with skin may cause dermatitis. Animal tests show that this substance possibly causes toxic effects upon human reproduction.
    PHYSICAL
    PROPERTIES
    Boiling point: 202C
    Melting point: -24C
    Relative density (water = 1): 1.03
    Solubility in water: very good
    Vapour pressure, Pa at 25C: 66
    Relative vapour density (air = 1): 3.4
    Relative density of the vapour/air-mixture at 20C (air = 1): 1.00
    Flash point: 96C o.c.
    Auto-ignition temperature: 270C
    Explosive limits, vol% in air: 0.99-3.9
    ENVIRONMENTAL
    DATA

    N O T E S
    N-Methyl-2-pyrrolidone enhances the skin permeability for other substances. Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken.
    NFPA Code: H2; F1; R0.
    ADDITIONAL INFORMATION


    ICSC: 0513 N-METHYL-2-PYRROLIDONE
    © IPCS, CEC, 1993
    IMPORTANT LEGAL NOTICE: Neither the CEC or the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use.