MSDS Number: P6928 --- Effective Date: 12/08/96

1. Product Identification

Synonyms: 1,2-propanediol; 1,2-dihdroxypropane; methyl glycol; methylethylene glycol
CAS No.: 57-55-6
Molecular Weight: 76.09
Chemical Formula: CH3CHOHCH2OH
Product Codes: J.T. Baker: 9402, U510 Mallinckrodt: 1925, 6263

2. Composition/Information on Ingredients

  Ingredient                                CAS No         Percent   Hazardous                                       
  ---------------------------------------   ------------   -------   ---------        
  Propylene Glycol                          57-55-6        99 - 100%    Yes                                                                  

3. Hazards Identification

Emergency Overview

J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
Health Rating: 0 - None
Flammability Rating: 1 - Slight
Reactivity Rating: 1 - Slight
Contact Rating: 2 - Moderate
Lab Protective Equip: GOGGLES; LAB COAT
Storage Color Code: Orange (General Storage)

Potential Health Effects

No adverse health effects via inhalation.

Relatively non-toxic. Ingestion of sizable amount (over 100ml) may cause some gastrointestinal upset and temporary central nervous system depression. Effects appear more severe in individuals with kidney problems.

Skin Contact:
Mild irritant and defatting agent, especially on prolonged contact.

Eye Contact:
May cause transitory stinging and tearing.

Chronic Exposure:
Lactic acidosis, stupor and seizures have been reported following chronic ingestion.

Aggravation of Pre-existing Conditions:
Kidney disorders.

4. First Aid Measures

Remove to fresh air. Not expected to require first aid measures.

Not expected to require first aid measures. Give several glasses of water to drink to dilute. If large amounts were swallowed, get medical advice.

Skin Contact:
Remove any contaminated clothing. Wash skin with soap and water for at least 15 minutes. Get medical attention if irritation develops or persists.

Eye Contact:
In case of contact, immediately flush eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids occasionally. Call a physician if irritation persists.

Note to Physician:
In case of ingestion, monitor for acidosis and central nervous system changes. Exposed persons with previous kidney dysfunction may require special treatment.

5. Fire Fighting Measures

Flash point: 99C (210F) CC Autoignition temperature: 371C (700F) Flammable limits in air % by volume: lel: 2.6; uel: 12.5 Material can support combustion.

Containers may explode in heat or fire.

Fire Extinguishing Media:
Dry chemical, foam, water or carbon dioxide.

Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. Move exposed containers from fire area, if it can be done without risk. Use water to keep fire-exposed containers cool.

6. Accidental Release Measures

Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel from entering. Contain and recover liquid when possible. Use non-sparking tools and equipment. Collect liquid in an appropriate container or absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a chemical waste container. Do not use combustible materials, such as saw dust. Do not flush to sewer!

7. Handling and Storage

Protect container from physical damage. Store in a cool, dry, ventilated area away from sources of heat, moisture, and incompatible substances. Containers of this material may be hazardous when empty since they retain product residues (vapors, liquid); observe all warnings and precautions listed for the product.

8. Exposure Controls/Personal Protection

Airborne Exposure Limits:
AIHA Workplace Environmental Exposure Level (WEEL): Vapor and Aerosol = 50ppm; Aerosol, only = 10mg/m3.

Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.

Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded, a half-face respirator with an organic vapor cartridge and dust/mist filter may be worn for up to ten times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. A full-face piece respirator with an organic vapor cartridge and dust/mist filter may be worn up to 50 times the exposure limit, or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a full-face piece positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.

Skin Protection:
Wear protective gloves and clean body-covering clothing.

Eye Protection:
Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.

9. Physical and Chemical Properties

Clear oily liquid.


Miscible in water.

Specific Gravity:
0.0361 @ 20C/4C

No information found.

% Volatiles by volume @ 21C (70F):
No information found.

Boiling Point:
188.2C (370F)

Melting Point:
-59C (-74F)

Vapor Density (Air=1):

Vapor Pressure (mm Hg):
0.129 @ 25C (77F)

Evaporation Rate (BuAc=1):

10. Stability and Reactivity

Stable under ordinary conditions of use and storage.

Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition. Aldehydes or lactic, pyruvic or acetic acids may also be formed.

Hazardous Polymerization:
Will not occur.

Strong oxidizing agents.

Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.

11. Toxicological Information

Oral rat LD50: 20g/kg. Skin rabbit LD50: 20.8g/kg. Irritation: Eye rabbit/Draize, 500 mg/24H mild. Investigated as a mutagen and reproductive effector.

  --------\Cancer Lists\------------------------------------------------------
                                         ---NTP Carcinogen---
  Ingredient                             Known    Anticipated    IARC Category
  ------------------------------------   -----    -----------    -------------
  Propylene Glycol (57-55-6)              No          No            None

12. Ecological Information

Environmental Fate:
When released into the soil, this material is expected to readily biodegrade. When released into the soil, this material is expected to leach into groundwater. When released into water, this material is expected to readily biodegrade. When released into the air, this material is expected to be readily degraded by reaction with photochemically produced hydroxyl radicals. When released into the air, this material is expected to have a half-life between 1 and 10 days.

Environmental Toxicity:
No information found.

13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.

14. Transport Information

Not regulated.

15. Regulatory Information

  --------\Chemical Inventory Status - Part 1\---------------------------------
  Ingredient                                       TSCA  EC   Japan  Australia
  -----------------------------------------------  ----  ---  -----  ---------
  Propylene Glycol (57-55-6)                        Yes  Yes   Yes      Yes                                      
  --------\Chemical Inventory Status - Part 2\---------------------------------
  Ingredient                                       Korea  DSL   NDSL  Phil.
  -----------------------------------------------  -----  ---   ----  -----
  Propylene Glycol (57-55-6)                        Yes   Yes   No     Yes                             
  --------\Federal, State & International Regulations - Part 1\----------------
                                             -SARA 302-    ------SARA 313------
  Ingredient                                 RQ    TPQ     List  Chemical Catg.
  -----------------------------------------  ---   -----   ----  --------------
  Propylene Glycol (57-55-6)                 No    No      No         No
  --------\Federal, State & International Regulations - Part 2\----------------
                                                        -RCRA-    -TSCA-
  Ingredient                                 CERCLA     261.33     8(d) 
  -----------------------------------------  ------     ------    ------
  Propylene Glycol (57-55-6)                 No         No         No                   
Chemical Weapons Convention:  No     TSCA 12(b):  No     CDTA:  No
SARA 311/312:  Acute: Yes      Chronic: No   Fire: No  Pressure: No
Reactivity: No          (Pure / Liquid)

Australian Hazchem Code: No information found.
Poison Schedule: No information found.

This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.

16. Other Information

NFPA Ratings: Health: 0 Flammability: 1 Reactivity: 0

Label Hazard Warning:

Label Precautions:
Avoid contact with eyes, skin and clothing. Wash thoroughly after handling.

Label First Aid:
In case of contact, immediately flush skin or eyes with plenty of water for at least 15 minutes. Call a physician if irritation develops or persists.

Product Use:
Laboratory Reagent.

Revision Information:
Pure. New 16 section MSDS format, all sections have been revised.

************************************************************************************************ Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
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Phone Number: (314) 539-1600 (U.S.A.)